cox7a2a cytochrome c oxidase subunit 7A2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cox7a2aprovided by ZNC
Official Full Name: cytochrome c oxidase subunit 7A2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-153
See related: Ensembl:ENSDARG00000053217 AllianceGenome:ZFIN:ZDB-GENE-050522-153
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cox7a2; wu:fa66a01; zgc:109970
Summary: Predicted to be involved in mitochondrial respirasome assembly and regulation of oxidative phosphorylation. Predicted to act upstream of or within mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex. Orthologous to several human genes including COX7A2 (cytochrome c oxidase subunit 7A2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (49983157..49995366, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (49883252..49895461, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within mitochondrial electron transport, cytochrome c to oxygen	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial respirasome assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of oxidative phosphorylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytochrome c oxidase subunit 7A2a

Names: cytochrome c oxidase subunit VIIa polypeptide 2a (liver); cytochrome c oxidase, subunit VIIa 2; cytochrome c oxidase, subunit VIIa 2a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001032728.1 → NP_001027900.1 cytochrome c oxidase subunit 7A2a

See identical proteins and their annotated locations for NP_001027900.1

Status: PROVISIONAL

Source sequence(s)

BC095093

UniProtKB/TrEMBL

Q504B4

Related

ENSDARP00000069708.3, ENSDART00000075223.6

Conserved Domains (1) summary

cd00928
Location:24 → 78

Cyt_c_Oxidase_VIIa; Cytochrome c oxidase subunit VIIa. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...