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    fkbp2 FKBP prolyl isomerase 2 [ Danio rerio (zebrafish) ]

    Gene ID: 447939, updated on 9-Dec-2024

    Summary

    Official Symbol
    fkbp2provided by ZNC
    Official Full Name
    FKBP prolyl isomerase 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-126
    See related
    Ensembl:ENSDARG00000044540 AllianceGenome:ZFIN:ZDB-GENE-040912-126
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:101826
    Summary
    Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to act upstream of or within chaperone-mediated protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in endoplasmic reticulum. Orthologous to human FKBP2 (FKBP prolyl isomerase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See fkbp2 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (26991196..26996037)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (26954501..26959342)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene pyruvate carboxylase a Neighboring gene uncharacterized LOC101883097 Neighboring gene uncharacterized LOC101883049 Neighboring gene leucine rich repeat and fibronectin type III domain containing 4a Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14Ba Neighboring gene solute carrier family 8 member 4a Neighboring gene BCL2 associated agonist of cell death a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within chaperone-mediated protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    peptidyl-prolyl cis-trans isomerase FKBP2
    Names
    FK506 binding protein 2
    NP_001004677.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004677.2NP_001004677.2  peptidyl-prolyl cis-trans isomerase FKBP2 precursor

      See identical proteins and their annotated locations for NP_001004677.2

      Status: VALIDATED

      Source sequence(s)
      BX465183, EH538052, EH560251
      UniProtKB/TrEMBL
      A0A8M1N2D2, A9JSW0
      Related
      ENSDARP00000065396.4, ENSDART00000065397.6
      Conserved Domains (1) summary
      pfam00254
      Location:38130
      FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      26991196..26996037
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)