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    trnau1apb tRNA selenocysteine 1 associated protein 1b [ Danio rerio (zebrafish) ]

    Gene ID: 791478, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trnau1apbprovided by ZNC
    Official Full Name
    tRNA selenocysteine 1 associated protein 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2386
    See related
    Ensembl:ENSDARG00000056475 AllianceGenome:ZFIN:ZDB-GENE-040426-2386
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    secpl; secp43; trspap1; trnau1ap; trnau1apl; zgc:77884; wu:fa56b07; wu:fc12c07; wu:fc69f09; zgc:113964
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Orthologous to human TRNAU1AP (tRNA selenocysteine 1 associated protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See trnau1apb in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (24310635..24317228, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (24654984..24661600, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene myosin heavy chain 7-like Neighboring gene fat storage inducing transmembrane protein 1, like Neighboring gene mitochondrial ribosomal protein L34 Neighboring gene anoctamin 8a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Zebrafish (Danio rerio) vary by strain and sex in their behavioral and transcriptional responses to selenium supplementation. Benner MJ, et al. Comp Biochem Physiol A Mol Integr Physiol, 2010 Dec. PMID 20659579, Free PMC Article
    2. Roles of selenoprotein antioxidant protection in zebrafish, Danio rerio, subjected to dietary oxidative stress. Betancor MB, et al. Fish Physiol Biochem, 2015 Jun. PMID 25750091
    3. Sex-specific transcriptional responses of the zebrafish (Danio rerio) brain selenoproteome to acute sodium selenite supplementation. Benner MJ, et al. Physiol Genomics, 2013 Aug 1. PMID 23737534, Free PMC Article
    4. Dietary Seleno-l-Methionine Causes Alterations in Neurotransmitters, Ultrastructure of the Brain, and Behaviors in Zebrafish (Danio rerio). Li X, et al. Environ Sci Technol, 2021 Sep 7. PMID 34488355
    5. Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury. Penglase S, et al. Free Radic Biol Med, 2014 Oct. PMID 25064324

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77884, MGC113964

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tRNA selenocysteine 1-associated protein 1-like
    Names
    tRNA selenocysteine 1 associated protein 1, like
    tRNA selenocysteine 1-associated protein 1
    tRNA selenocysteine associated protein 1, like
    tRNA selenocysteine-associated protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001029966.2 → NP_001025137.2  tRNA selenocysteine 1-associated protein 1-like

      Status: VALIDATED

      Source sequence(s)
      AI601817, BQ450001, CB356560, CV489023, CV489035, EB769378
      UniProtKB/Swiss-Prot
      Q4KM14
      UniProtKB/TrEMBL
      A0A8M1N7C7, F1QXG2
      Related
      ENSDARP00000073432.3, ENSDART00000078975.4
      Conserved Domains (2) summary
      cd12610
      Location:7 → 90
      RRM1_SECp43; RNA recognition motif 1 in tRNA selenocysteine-associated protein 1 (SECp43)
      cd12612
      Location:98 → 179
      RRM2_SECp43; RNA recognition motif 2 in tRNA selenocysteine-associated protein 1 (SECp43)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      24310635..24317228 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_213251.1: Suppressed sequence

      Description
      NM_213251.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4KM14.1 GenPept UniProtKB/Swiss-Prot:Q4KM14

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.