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    ppp1r3b protein phosphatase 1, regulatory subunit 3B [ Danio rerio (zebrafish) ]

    Gene ID: 327285, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ppp1r3bprovided by ZNC
    Official Full Name
    protein phosphatase 1, regulatory subunit 3Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5496
    See related
    Ensembl:ENSDARG00000044691 AllianceGenome:ZFIN:ZDB-GENE-030131-5496
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55542; wu:fd20c10; wu:fi66d07
    Summary
    Predicted to enable glycogen binding activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to act upstream of or within glycogen metabolic process and regulation of glycogen catabolic process. Predicted to be part of protein phosphatase type 1 complex. Orthologous to human PPP1R3B (protein phosphatase 1 regulatory subunit 3B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ppp1r3b in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (19916459..19919898, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (19879820..19883344, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene multifunctional ROCO family signaling regulator 1 Neighboring gene exoribonuclease 1 Neighboring gene tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a Neighboring gene dual specificity phosphatase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. NEFLb impairs early nervous system development via regulation of neuron apoptosis in zebrafish. Wang S, et al. J Cell Physiol, 2019 Jul. PMID 30569449
    2. In vivo imaging of calcium dynamics in zebrafish hepatocytes. Pozo-Morales M, et al. Hepatology, 2023 Mar 1. PMID 35829917
    3. Molecular Toxicity of Metal Oxide Nanoparticles in Danio rerio. Hou J, et al. Environ Sci Technol, 2018 Jul 17. PMID 29944347
    4. Analyses of mRNA structure dynamics identify embryonic gene regulatory programs. Beaudoin JD, et al. Nat Struct Mol Biol, 2018 Aug. PMID 30061596, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables glycogen binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein phosphatase 1 binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within glycogen metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of glycogen biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of glycogen catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein phosphatase type 1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein phosphatase type 1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase 1 regulatory subunit 3B
    Names
    protein phosphatase 1, regulatory (inhibitor) subunit 3B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212709.1 → NP_997874.1  protein phosphatase 1 regulatory subunit 3B

      See identical proteins and their annotated locations for NP_997874.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044421
      UniProtKB/Swiss-Prot
      Q803M0
      Related
      ENSDARP00000065669.5, ENSDART00000065670.6
      Conserved Domains (1) summary
      pfam03370
      Location:131 → 236
      CBM_21; Carbohydrate/starch-binding module (family 21)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      19916459..19919898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005161147.5 → XP_005161204.1  protein phosphatase 1 regulatory subunit 3B isoform X1

      UniProtKB/TrEMBL
      A0A8M2B8D4
      Conserved Domains (1) summary
      pfam03370
      Location:146 → 251
      CBM_21; Carbohydrate/starch-binding module (family 21)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395088.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      45064..48472 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395348.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      45087..48494 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q803M0.1 GenPept UniProtKB/Swiss-Prot:Q803M0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.