slc13a2 solute carrier family 13 member 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc13a2provided by ZNC
Official Full Name: solute carrier family 13 member 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2389
See related: Ensembl:ENSDARG00000053853 AllianceGenome:ZFIN:ZDB-GENE-040426-2389
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55601; zgc:77607; wu:fd51b01; wu:fi13d08; wu:fi31b05
Summary: Predicted to enable dicarboxylic acid transmembrane transporter activity. Predicted to be involved in cellular response to lithium ion and dicarboxylic acid transport. Predicted to act upstream of or within sodium ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human SLC13A2 (solute carrier family 13 member 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 21

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (39100369..39118502)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (39055311..39073444)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fd51b01.x1 (e-PCR)
- UniSTS:195597

fi31b05.x1 (e-PCR)
- UniSTS:197255

fi13d08.x1 (e-PCR)
- UniSTS:196820

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables alpha-ketoglutarate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables fumarate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables sodium:dicarboxylate symporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables succinate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in alpha-ketoglutarate transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to lithium ion	IBA Inferred from Biological aspect of Ancestor more info
involved_in fumarate transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sodium ion transport	IEA Inferred from Electronic Annotation more info
involved_in succinate transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: solute carrier family 13 member 2

Names: solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213452.2 → NP_998617.2 solute carrier family 13 member 2

See identical proteins and their annotated locations for NP_998617.2

Status: PROVISIONAL

Source sequence(s)

BC063947

UniProtKB/TrEMBL

Q6P3L2

Related

ENSDARP00000070437.4, ENSDART00000075958.5

Conserved Domains (2) summary

TIGR00785
Location:45 → 588

dass; anion transporter

cl21473
Location:40 → 595

ArsB_NhaD_permease; Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...