hpf1 histone PARylation factor 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hpf1provided by ZNC
Official Full Name: histone PARylation factor 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-740
See related: Ensembl:ENSDARG00000057114 AllianceGenome:ZFIN:ZDB-GENE-030131-740
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb44b08; wu:fb44b08; zgc:101819
Summary: Predicted to enable several functions, including histone binding activity; poly-ADP-D-ribose binding activity; and protein ADP-ribosyltransferase-substrate adaptor activity. Predicted to be involved in DNA repair-dependent chromatin remodeling and double-strand break repair. Predicted to act upstream of or within DNA repair. Predicted to be located in chromatin and site of DNA damage. Predicted to be active in nucleus. Is expressed in brain; ovary; and testis. Orthologous to human HPF1 (histone PARylation factor 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (14020445..14026781)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (13333932..13340268)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb44b08 (e-PCR)
- UniSTS:187210

fb44b08.x1 (e-PCR)
- UniSTS:203209

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables chromatin binding	ISS Inferred from Sequence or Structural Similarity more info
enables histone binding	IBA Inferred from Biological aspect of Ancestor more info
enables histone binding	IEA Inferred from Electronic Annotation more info
enables poly-ADP-D-ribose binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein ADP-ribosyltransferase-substrate adaptor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
involved_in DNA repair-dependent chromatin remodeling	IBA Inferred from Biological aspect of Ancestor more info
involved_in DNA repair-dependent chromatin remodeling	ISS Inferred from Sequence or Structural Similarity more info
involved_in double-strand break repair	IBA Inferred from Biological aspect of Ancestor more info
involved_in double-strand break repair	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in chromatin	ISS Inferred from Sequence or Structural Similarity more info
located_in chromosome	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
located_in site of DNA damage	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: histone PARylation factor 1

Names: UPF0609 protein C4orf27 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.