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    zfand5a zinc finger, AN1-type domain 5a [ Danio rerio (zebrafish) ]

    Gene ID: 406312, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zfand5aprovided by ZNC
    Official Full Name
    zinc finger, AN1-type domain 5aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1979
    See related
    Ensembl:ENSDARG00000018898 AllianceGenome:ZFIN:ZDB-GENE-040426-1979
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    za20d2; zgc:73363; id:ibd2892; wu:fb16d02; wu:fc67h07
    Summary
    Predicted to enable DNA binding activity and zinc ion binding activity. Is expressed in several structures, including blastomere; brain; mesenchyme; mesoderm; and tail bud. Orthologous to human ZFAND5 (zinc finger AN1-type containing 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See zfand5a in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (25680839..25694359)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (25080691..25094206)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 1, subfamily D, polypeptide 1 Neighboring gene transmembrane channel-like 2b Neighboring gene transmembrane channel-like 1 Neighboring gene guanine deaminase Neighboring gene zgc:101016

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The TATA-binding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish. Ferg M, et al. EMBO J, 2007 Sep 5. PMID 17703193, Free PMC Article
    2. Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas. Liu Z, et al. J Biol Chem, 2011 Aug 12. PMID 21669877, Free PMC Article
    3. Protein palmitoylation activate zygotic gene expression during the maternal-to-zygotic transition. Du Z, et al. Biochem Biophys Res Commun, 2016 Jun 24. PMID 27235108
    4. Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes. Cañestro C, et al. PLoS Genet, 2009 May. PMID 19478994, Free PMC Article
    5. A gene expression screen in zebrafish embryogenesis. Kudoh T, et al. Genome Res, 2001 Dec. PMID 11731487

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    AN1-type zinc finger protein 5a
    Names
    zfand5
    zinc finger, A20 domain containing 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213039.1 → NP_998204.1  AN1-type zinc finger protein 5a

      See identical proteins and their annotated locations for NP_998204.1

      Status: PROVISIONAL

      Source sequence(s)
      BC059673
      UniProtKB/TrEMBL
      A0A8M9PJU3, Q6PBK7
      Related
      ENSDARP00000019037.6, ENSDART00000009952.9
      Conserved Domains (2) summary
      smart00154
      Location:154 → 191
      ZnF_AN1; AN1-like Zinc finger
      pfam01754
      Location:12 → 35
      zf-A20; A20-like zinc finger

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      25680839..25694359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005171826.5 → XP_005171883.1  AN1-type zinc finger protein 5a isoform X1

      UniProtKB/TrEMBL
      A0A8M2BJ38, A2BFW0
      Related
      ENSDARP00000117816.1, ENSDART00000139701.3
      Conserved Domains (3) summary
      smart00154
      Location:155 → 192
      ZnF_AN1; AN1-like Zinc finger
      pfam01754
      Location:12 → 35
      zf-A20; A20-like zinc finger
      cl26247
      Location:41 → 136
      DNA_pol3_delta2; DNA polymerase III, delta subunit

    2. XM_021476056.2 → XP_021331731.1  AN1-type zinc finger protein 5a isoform X1

      UniProtKB/TrEMBL
      A0A8M2BJ38, A2BFW0
      Conserved Domains (3) summary
      smart00154
      Location:155 → 192
      ZnF_AN1; AN1-like Zinc finger
      pfam01754
      Location:12 → 35
      zf-A20; A20-like zinc finger
      cl26247
      Location:41 → 136
      DNA_pol3_delta2; DNA polymerase III, delta subunit

    3. XM_021476057.2 → XP_021331732.1  AN1-type zinc finger protein 5a isoform X2

      UniProtKB/TrEMBL
      A0A8M9PJU3, Q6PBK7
      Related
      ENSDARP00000113136.1, ENSDART00000134773.2
      Conserved Domains (2) summary
      smart00154
      Location:154 → 191
      ZnF_AN1; AN1-like Zinc finger
      pfam01754
      Location:12 → 35
      zf-A20; A20-like zinc finger
    Nucleotide Protein Strain
    Heading Accession and Version

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