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    rabif RAB interacting factor [ Danio rerio (zebrafish) ]

    Gene ID: 436784, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rabifprovided by ZNC
    Official Full Name
    RAB interacting factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-216
    See related
    Ensembl:ENSDARG00000002690 AllianceGenome:ZFIN:ZDB-GENE-040718-216
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92821; wu:fc54e04
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity and zinc ion binding activity. Predicted to be involved in post-Golgi vesicle-mediated transport. Predicted to act upstream of or within protein transport and small GTPase-mediated signal transduction. Predicted to be active in cytosol and membrane. Orthologous to human RABIF (RAB interacting factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rabif in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (24815648..24817763)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (24578032..24580147)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene cytochrome b5 reductase 1 Neighboring gene adiponectin receptor 1a Neighboring gene lysine demethylase 5Ba Neighboring gene importin 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation. Nishio S, et al. Dev Dyn, 2008 Jun. PMID 18489000
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in post-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    guanine nucleotide exchange factor MSS4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002511.2 → NP_001002511.1  guanine nucleotide exchange factor MSS4

      See identical proteins and their annotated locations for NP_001002511.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      CR628365
      UniProtKB/TrEMBL
      A0A8M1NW93, Q6DGQ2
      Related
      ENSDARP00000102249.2, ENSDART00000115356.4
      Conserved Domains (1) summary
      pfam04421
      Location:43 → 131
      Mss4; Mss4 protein

    2. NM_001168213.2 → NP_001161685.2  guanine nucleotide exchange factor MSS4

      See identical proteins and their annotated locations for NP_001161685.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      CR628365
      UniProtKB/TrEMBL
      A0A8M1NW93, Q6DGQ2
      Conserved Domains (1) summary
      pfam04421
      Location:43 → 131
      Mss4; Mss4 protein

    3. NM_001198741.1 → NP_001185670.1  guanine nucleotide exchange factor MSS4

      See identical proteins and their annotated locations for NP_001185670.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      CR628365
      UniProtKB/TrEMBL
      A0A8M1NW93, Q6DGQ2
      Related
      ENSDARP00000121226.1, ENSDART00000142327.2
      Conserved Domains (1) summary
      pfam04421
      Location:43 → 131
      Mss4; Mss4 protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      24815648..24817763
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394821.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      1622..3737
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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