U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    letm2 leucine zipper-EF-hand containing transmembrane protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 100006201, updated on 9-Dec-2024

    Summary

    Official Symbol
    letm2provided by ZNC
    Official Full Name
    leucine zipper-EF-hand containing transmembrane protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090521-4
    See related
    Ensembl:ENSDARG00000077515 AllianceGenome:ZFIN:ZDB-GENE-090521-4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in mitochondrial calcium ion transmembrane transport and mitochondrion organization. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human LETM2 (leucine zipper and EF-hand containing transmembrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See letm2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (20590286..20605721)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (20632819..20648340)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene phospholipid phosphatase 5 Neighboring gene nuclear receptor binding SET domain protein 3 Neighboring gene si:dkey-81j8.6 Neighboring gene prion protein b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ribosome binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial calcium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    LETM1 domain-containing protein LETM2, mitochondrial
    Names
    let-m2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      20590286..20605721
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001339351.9XP_001339387.1  LETM1 domain-containing protein LETM2, mitochondrial

      UniProtKB/TrEMBL
      A0A8M1PZB6, F1QSQ8
      Related
      ENSDARP00000122053.1, ENSDART00000131819.2
      Conserved Domains (1) summary
      pfam07766
      Location:121358
      LETM1; LETM1-like protein

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394780.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      506..4717
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_002457261.2 RNA Sequence