clta clathrin, light chain A [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cltaprovided by ZNC
Official Full Name: clathrin, light chain Aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1986
See related: Ensembl:ENSDARG00000045618 AllianceGenome:ZFIN:ZDB-GENE-040426-1986
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73358; wu:fb61d08; wu:fj48d06
Summary: Predicted to enable clathrin heavy chain binding activity. Predicted to be involved in clathrin-dependent endocytosis. Predicted to act upstream of or within intracellular protein transport and vesicle-mediated transport. Predicted to be located in clathrin-coated pit and cytoplasmic vesicle. Predicted to be part of clathrin vesicle coat. Predicted to be active in plasma membrane; postsynaptic endocytic zone cytoplasmic component; and synaptic vesicle membrane. Orthologous to human CLTA (clathrin light chain A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (12348242..12361930)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (11661417..11675130)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The development of transgenic zebrafish lines expressing CLTA fused to dsRed and CAV1 fused to GFP is reported.
Title: Novel transgenic lines to fluorescently label clathrin and caveolin endosomes in live zebrafish.

Submit: New GeneRIF Correction

General gene information

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Markers

fb61d08.x1 (e-PCR)
- UniSTS:203381

fb61d08 (e-PCR)
- UniSTS:187300

fj48d06.x1 (e-PCR)
- UniSTS:188619

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables clathrin heavy chain binding	IBA Inferred from Biological aspect of Ancestor more info
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in clathrin-dependent endocytosis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of clathrin coat of coated pit	IEA Inferred from Electronic Annotation more info
part_of clathrin coat of trans-Golgi network vesicle	IEA Inferred from Electronic Annotation more info
part_of clathrin vesicle coat	IBA Inferred from Biological aspect of Ancestor more info
located_in clathrin-coated pit	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in postsynaptic endocytic zone cytoplasmic component	IBA Inferred from Biological aspect of Ancestor more info
is_active_in synaptic vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: clathrin light chain A

Names: clathrin, light chain (Lca); clathrin, light polypeptide (Lca)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213045.1 → NP_998210.1 clathrin light chain A

See identical proteins and their annotated locations for NP_998210.1

Status: PROVISIONAL

Source sequence(s)

BC060939

UniProtKB/TrEMBL

A0A8M1PIK9, Q6P937

Related

ENSDARP00000067081.4, ENSDART00000067082.5

Conserved Domains (1) summary

pfam01086
Location:1 → 234

Clathrin_lg_ch; Clathrin light chain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007112.7 Reference GRCz11 Primary Assembly

Range

12348242..12361930

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005159805.4 → XP_005159862.1 clathrin light chain A isoform X1

UniProtKB/TrEMBL

A0A8M2B6P8, E9QDE6

Related

ENSDARP00000114058.1, ENSDART00000138759.3

Conserved Domains (1) summary

pfam01086
Location:1 → 222

Clathrin_lg_ch; Clathrin light chain
XM_005159806.4 → XP_005159863.1 clathrin light chain A isoform X2

UniProtKB/TrEMBL

A0A8M2B6L7, E7F1Q8, E9QI07

Related

ENSDARP00000113917.1, ENSDART00000144920.3

Conserved Domains (1) summary

pfam01086
Location:1 → 204

Clathrin_lg_ch; Clathrin light chain