maff v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: maffprovided by ZNC
Official Full Name: v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Fprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1280
See related: Ensembl:ENSDARG00000028957 AllianceGenome:ZFIN:ZDB-GENE-040426-1280
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:63868
Summary: Enables DNA binding activity and protein heterodimerization activity. Contributes to DNA-binding transcription factor activity. Acts upstream of or within positive regulation of DNA-templated transcription. Part of transcription regulator complex. Orthologous to human MAFF (MAF bZIP transcription factor F). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 12

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (19340786..19346647, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (19218758..19224773, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

results indicated that MafT is a new member of small Maf proteins and involved in the Nrf2-dependent gene regulation in cellular defense system [MafT]
Title: MafT, a new member of the small Maf protein family in zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA binding	IEA Inferred from Electronic Annotation more info
contributes_to DNA binding	IPI Inferred from Physical Interaction more info	PubMed
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
contributes_to DNA-binding transcription factor activity	IGI Inferred from Genetic Interaction more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein heterodimerization activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of epidermal cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription regulator complex	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: transcription factor MafF

Names: v-maf musculoaponeurotic fibrosarcoma oncogene homolog f

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200336.1 → NP_956630.1 transcription factor MafF

See identical proteins and their annotated locations for NP_956630.1

Status: PROVISIONAL

Source sequence(s)

BC053121

UniProtKB/TrEMBL

F6NVN7, Q6I6M9, Q7T3H0

Related

ENSDARP00000044859.5, ENSDART00000044860.6

Conserved Domains (2) summary

cd14717
Location:46 → 115

bZIP_Maf_small; coiled coil [structural motif]

pfam03131
Location:24 → 115

bZIP_Maf; bZIP Maf transcription factor