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    icn ictacalcin [ Danio rerio (zebrafish) ]

    Gene ID: 336655, updated on 9-Dec-2024

    Summary

    Official Symbol
    icnprovided by ZNC
    Official Full Name
    ictacalcinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8599
    See related
    Ensembl:ENSDARG00000009978 AllianceGenome:ZFIN:ZDB-GENE-030131-8599
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fa91d07; s100a4a; mg:cb02f02; wu:fa91d07
    Summary
    Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Predicted to be active in cytoplasm. Is expressed in several structures, including digestive system; fin; hematopoietic system; integument; and sensory system. Orthologous to several human genes including S100A4 (S100 calcium binding protein A4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See icn in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (23431180..23432552)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (23516148..23517520)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene S100 calcium binding protein A10b Neighboring gene S100 calcium binding protein W Neighboring gene ictacalcin 2 Neighboring gene sorting nexin 27b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC123122

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables calcium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables calcium-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transition metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ictacalcin
    Names
    S100 calcium binding protein A4a
    calvasculin
    metastasin
    s100i1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212761.2NP_997926.1  ictacalcin

      See identical proteins and their annotated locations for NP_997926.1

      Status: VALIDATED

      Source sequence(s)
      BC107522, CR533578
      UniProtKB/TrEMBL
      F6NZN2, Q3B7P2, Q6XG62
      Related
      ENSDARP00000020595.7, ENSDART00000004679.8
      Conserved Domains (2) summary
      cd00213
      Location:491
      S-100; S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 ...
      pfam13499
      Location:2980
      EF-hand_7; EF-hand domain pair

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      23431180..23432552
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)