trim63b tripartite motif containing 63b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: trim63bprovided by ZNC
Official Full Name: tripartite motif containing 63bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1003
See related: Ensembl:ENSDARG00000086685 AllianceGenome:ZFIN:ZDB-GENE-040426-1003
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Rnf30; zgc:56376
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response. Predicted to be located in Z disc. Predicted to be active in cytoplasm. Is expressed in brain; cardiovascular system; gonad; and musculature system. Orthologous to human TRIM63 (tripartite motif containing 63). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 9

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (23900703..23902215)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (24089834..24091346)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in innate immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in Z disc	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein LOC394070

Names: MuRF1B

NP_957389.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201095.1 → NP_957389.1 uncharacterized protein LOC394070

See identical proteins and their annotated locations for NP_957389.1

Status: PREDICTED

Source sequence(s)

BC049414

UniProtKB/TrEMBL

Q7ZWH0

Related

ENSDARP00000109359.2, ENSDART00000127859.3

Conserved Domains (3) summary

cd00162
Location:25 → 76

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

pfam00643
Location:123 → 165

zf-B_box; B-box zinc finger

cl23765
Location:172 → 297

iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits