psmd11b proteasome 26S subunit, non-ATPase 11b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: psmd11bprovided by ZNC
Official Full Name: proteasome 26S subunit, non-ATPase 11bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-984
See related: Ensembl:ENSDARG00000005134 AllianceGenome:ZFIN:ZDB-GENE-030131-984
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: psmd11; zgc:56580; zgc:77763; wu:fb55b06
Summary: Predicted to enable structural molecule activity. Predicted to be involved in proteasome assembly; stem cell differentiation; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome regulatory particle, lid subcomplex. Orthologous to human PSMD11 (proteasome 26S subunit, non-ATPase 11). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 12

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (28349844..28363092, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (28234942..28248190, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb55b06.x1 (e-PCR)
- UniSTS:190724

fb57b03.y1 (e-PCR)
- UniSTS:190754

fb81d07.y1 (e-PCR)
- UniSTS:191620

AI477055 (e-PCR)
- UniSTS:206529

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables structural molecule activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in proteasome assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in stem cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in ubiquitin-dependent protein catabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of proteasome accessory complex	ISS Inferred from Sequence or Structural Similarity more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 11B

Names: 26S proteasome regulatory subunit RPN6-B; proteasome (prosome, macropain) 216S subunit, non-ATPase, 11b; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199592.1 → NP_955886.1 26S proteasome non-ATPase regulatory subunit 11B

See identical proteins and their annotated locations for NP_955886.1

Status: PROVISIONAL

Source sequence(s)

BC051618

UniProtKB/Swiss-Prot

F1QGH9, Q7ZTZ8

Related

ENSDARP00000020942.7, ENSDART00000016283.9

Conserved Domains (2) summary

COG5159
Location:17 → 421

RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]

pfam01399
Location:285 → 389

PCI; PCI domain