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    lonrf4 LON peptidase N-terminal domain and ring finger 4 [ Danio rerio (zebrafish) ]

    Gene ID: 560773, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lonrf4provided by ZNC
    Official Full Name
    LON peptidase N-terminal domain and ring finger 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-101021-4
    See related
    Ensembl:ENSDARG00000075048 AllianceGenome:ZFIN:ZDB-GENE-101021-4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    lonrf1; si:ch1073-193f3.1
    Summary
    Predicted to enable ubiquitin protein ligase activity. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See lonrf4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (34068069..34091017)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (33727748..33752431)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene IL2 inducible T cell kinase Neighboring gene mediator complex subunit 7 Neighboring gene glutamate receptor, ionotropic, AMPA 1a Neighboring gene uncharacterized LOC137487601

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Thyrotroph embryonic factor regulates light-induced transcription of repair genes in zebrafish embryonic cells. Gavriouchkina D, et al. PLoS One, 2010 Sep 7. PMID 20830285, Free PMC Article
    2. The light responsive transcriptome of the zebrafish: function and regulation. Weger BD, et al. PLoS One, 2011 Feb 15. PMID 21390203, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    LON peptidase N-terminal domain and RING finger protein 1
    Names
    LON peptidase N-terminal domain and ring finger 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      34068069..34091017
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021481225.2 → XP_021336900.1  LON peptidase N-terminal domain and RING finger protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PSI9, A0A8M9QPJ1, E9QIP2
      Related
      ENSDARP00000113687.1, ENSDART00000135556.4
      Conserved Domains (4) summary
      sd00006
      Location:108 → 138
      TPR; TPR repeat [structural motif]
      cd16514
      Location:303 → 344
      RING2-HC_LONFs; RING finger 2, HC subclass, found in the LON peptidase N-terminal domain and RING finger proteins family
      cl17238
      Location:9 → 47
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
      cl19481
      Location:385 → 591
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain

    RNA

    1. XR_011006238.1 RNA Sequence

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394918.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      231242..255537
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_684170.10 → XP_689262.3  LON peptidase N-terminal domain and RING finger protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PSI9, A0A8M9QPJ1, E9QIP2
      Conserved Domains (4) summary
      sd00006
      Location:108 → 138
      TPR; TPR repeat [structural motif]
      cd16514
      Location:303 → 344
      RING2-HC_LONFs; RING finger 2, HC subclass, found in the LON peptidase N-terminal domain and RING finger proteins family
      cl17238
      Location:9 → 47
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
      cl19481
      Location:385 → 591
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain

    RNA

    1. XR_002457391.2 RNA Sequence

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395316.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      251473..264692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021474313.2 → XP_021329988.2  LON peptidase N-terminal domain and RING finger protein 1 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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