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    map1sa microtubule-associated protein 1Sa [ Danio rerio (zebrafish) ]

    Gene ID: 562808, updated on 9-Dec-2024

    Summary

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    Official Symbol
    map1saprovided by ZNC
    Official Full Name
    microtubule-associated protein 1Saprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3982
    See related
    Ensembl:ENSDARG00000060805 AllianceGenome:ZFIN:ZDB-GENE-030131-3982
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc62e12; wu:fc62e12; si:dkey-37m8.10
    Summary
    Predicted to enable actin binding activity and microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization; neuron projection development; and regulation of microtubule depolymerization. Predicted to be part of microtubule associated complex. Predicted to be active in several cellular components, including dendrite; microtubule; and neuronal cell body. Orthologous to human MAP1S (microtubule associated protein 1S). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See map1sa in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (36794680..36829022, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (36853929..36888285, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene interferon induced protein 44g Neighboring gene cocaine- and amphetamine-regulated transcript 1 Neighboring gene kininogen 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Expression of three P4-phospholipid flippases-atp11a, atp11b, and atp11c in zebrafish (Danio rerio). Hawkey-Noble A, et al. Gene Expr Patterns, 2020 Jun. PMID 32344036
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in axonogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in dendrite development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of microtubule depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of microtubule associated complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    microtubule-associated protein 1S
    Names
    microtubule-associated protein 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      36794680..36829022 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_686182.9 → XP_691274.3  microtubule-associated protein 1S

      UniProtKB/TrEMBL
      A0A0R4ISC3, A0A8N7T7I0
      Related
      ENSDARP00000137630.1, ENSDART00000170256.3
      Conserved Domains (1) summary
      cl26511
      Location:486 → 735
      Neuromodulin_N; Gap junction protein N-terminal region

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395125.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      2000..36342 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473552.2 → XP_021329227.1  microtubule-associated protein 1S

      UniProtKB/TrEMBL
      A0A0R4ISC3, A0A8N7T7I0
      Conserved Domains (1) summary
      cl26511
      Location:486 → 735
      Neuromodulin_N; Gap junction protein N-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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