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    pgm3 phosphoglucomutase 3 [ Danio rerio (zebrafish) ]

    Gene ID: 474321, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pgm3provided by ZNC
    Official Full Name
    phosphoglucomutase 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041024-13
    See related
    Ensembl:ENSDARG00000024654 AllianceGenome:ZFIN:ZDB-GENE-041024-13
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc08c11; fc39c03; zgc:91932; wu:fc08c11; wu:fc39c03
    Summary
    Predicted to enable phosphoacetylglucosamine mutase activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process and hemopoiesis. Predicted to act upstream of or within carbohydrate metabolic process. Is expressed in blood; intermediate cell mass of mesoderm; and notochord. Human ortholog(s) of this gene implicated in immunodeficiency 23 and teratoma. Orthologous to human PGM3 (phosphoglucomutase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See pgm3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (5784970..5795273, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (5776400..5786703, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene cyclin C Neighboring gene notochord granular surface Neighboring gene si:ch73-352p4.8 Neighboring gene forkhead box M1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Analysis of the goldfish Carassius auratus olfactory epithelium transcriptome reveals the presence of numerous non-olfactory GPCR and putative receptors for progestin pheromones. Kolmakov NN, et al. BMC Genomics, 2008 Sep 20. PMID 18803863, Free PMC Article
    2. Robustness analysis on interspecies interaction network for iron and glucose competition between Candida albicans and zebrafish during infection. Lin C, et al. BMC Syst Biol, 2014. PMID 25603810, Free PMC Article
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables intramolecular phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphoacetylglucosamine mutase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in UDP-N-acetylglucosamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    phosphoacetylglucosamine mutase
    NP_001007054.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007053.1 → NP_001007054.1  phosphoacetylglucosamine mutase

      See identical proteins and their annotated locations for NP_001007054.1

      Status: PROVISIONAL

      Source sequence(s)
      BC084691
      UniProtKB/TrEMBL
      A0A8M9Q5V4, Q5XFY0
      Related
      ENSDARP00000039986.6, ENSDART00000039987.7
      Conserved Domains (2) summary
      cd03086
      Location:23 → 530
      PGM3; PGM3 (phosphoglucomutase 3), also known as PAGM (phosphoacetylglucosamine mutase) and AGM1 (N-acetylglucosamine-phosphate mutase), is an essential enzyme found in eukaryotes that reversibly catalyzes the conversion of GlcNAc-6-phosphate into ...
      PLN02895
      Location:7 → 541
      PLN02895; phosphoacetylglucosamine mutase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      5784970..5795273 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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