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    taf6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor [ Danio rerio (zebrafish) ]

    Gene ID: 447818, updated on 9-Dec-2024

    Summary

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    Official Symbol
    taf6provided by ZNC
    Official Full Name
    TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-23
    See related
    Ensembl:ENSDARG00000102998 AllianceGenome:ZFIN:ZDB-GENE-040912-23
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92160; wu:fb83e08; wu:fj30b02
    Summary
    Predicted to enable transcription coactivator activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to act upstream of or within transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to human TAF6 (TATA-box binding protein associated factor 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See taf6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (53581485..53761950)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (52934910..53115353)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103911119 Neighboring gene uncharacterized LOC137495523 Neighboring gene uncharacterized LOC103911121 Neighboring gene uncharacterized LOC103911120 Neighboring gene si:dkey-184n3.2 Neighboring gene uncharacterized LOC137495636 Neighboring gene spermidine/spermine N1-acetyltransferase family member 2b Neighboring gene N-alpha-acetyltransferase 38, NatC auxiliary subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Quantitative mass spectrometry of TATA binding protein-containing complexes and subunit phosphorylations during the cell cycle. Pijnappel WP, et al. Proteome Sci, 2009 Dec 24. PMID 20034391, Free PMC Article
    2. A genome-wide map of circular RNAs in adult zebrafish. Sharma D, et al. Sci Rep, 2019 Mar 5. PMID 30837568, Free PMC Article
    3. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
    4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II general transcription initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA polymerase II preinitiation complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within transcription initiation at RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SAGA complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of SLIK (SAGA-like) complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transcription initiation factor TFIID subunit 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004557.1 → NP_001004557.1  transcription initiation factor TFIID subunit 6

      See identical proteins and their annotated locations for NP_001004557.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081612
      UniProtKB/TrEMBL
      A0A8M9Q351, Q66HZ5
      Related
      ENSDARP00000134854.1, ENSDART00000161751.3
      Conserved Domains (1) summary
      cd08050
      Location:15 → 378
      TAF6; TATA Binding Protein (TBP) Associated Factor 6 (TAF6) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      53581485..53761950
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476094.2 → XP_021331769.1  transcription initiation factor TFIID subunit 6 isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q351, Q66HZ5
      Conserved Domains (1) summary
      cd08050
      Location:15 → 378
      TAF6; TATA Binding Protein (TBP) Associated Factor 6 (TAF6) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex
    Nucleotide Protein Strain
    Heading Accession and Version

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