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    krt97 keratin 97 [ Danio rerio (zebrafish) ]

    Gene ID: 436656, updated on 9-Dec-2024

    Summary

    Official Symbol
    krt97provided by ZNC
    Official Full Name
    keratin 97provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-78
    See related
    Ensembl:ENSDARG00000000212 AllianceGenome:ZFIN:ZDB-GENE-040718-78
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb112; sb:cb112; sb:cb481; zgc:92061; wu:fa91g11
    Summary
    Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Is expressed in several structures, including EVL; fin; hatching gland; integument; and sensory system. Human ortholog(s) of this gene implicated in several diseases, including corneal dystrophy (multiple); ectodermal dysplasia (multiple); epidermolytic hyperkeratosis (multiple); focal nonepidermolytic palmoplantar keratoderma 1; and pachyonychia congenita. Orthologous to several human genes including KRT13 (keratin 13); KRT14 (keratin 14); and KRT15 (keratin 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See krt97 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (11756057..11759106)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (11726375..11729424)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene crystallin, gamma S1 Neighboring gene keratin 222 Neighboring gene keratin 96 Neighboring gene protein tyrosine phosphatase non-receptor type 4b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    keratin 97
    Names
    cytokeratin E7
    krt17
    type I keratin E7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002383.1NP_001002383.1  keratin 97

      See identical proteins and their annotated locations for NP_001002383.1

      Status: PROVISIONAL

      Source sequence(s)
      BC075874
      UniProtKB/TrEMBL
      A0A8M1N0G0, Q6DHU3
      Related
      ENSDARP00000096586.3, ENSDART00000105808.4
      Conserved Domains (1) summary
      pfam00038
      Location:78387
      Filament; Intermediate filament protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      11756057..11759106
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)