rarga retinoic acid receptor gamma a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rargaprovided by ZNC
Official Full Name: retinoic acid receptor gamma aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-980526-531
See related: Ensembl:ENSDARG00000034117 AllianceGenome:ZFIN:ZDB-GENE-980526-531
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rarg; NR1B3; rarg2; wu:fb01e02; wu:fb01f03; wu:fc35a09; etID33387.23; etID309710.23
Summary: Enables DNA binding activity. Involved in pharyngeal system development. Acts upstream of or within liver development. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; germ ring; gonad; mesoderm; and neural crest. Orthologous to human RARG (retinoic acid receptor gamma). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 23

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (35847200..35965288)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (35819727..35864932)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb01f03.y1 (e-PCR)
- UniSTS:189792

fc35a09.x1 (e-PCR)
- UniSTS:188035

fb01e02.x1 (e-PCR)
- UniSTS:202654

rarg (e-PCR), detects polymorphism
- UniSTS:205522

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nuclear receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables nuclear receptor activity	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within liver development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in pharyngeal system development	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in retinoic acid receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within retinoic acid receptor signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: retinoic acid receptor gamma-A

Names: NR1B3-A; RAR gamma; RAR-gamma-2; RAR-gamma-A; RARgamma-A; nr1b3a; nuclear receptor subfamily 1 group B member 3-A; retinoic acid receptor gamma-2; zRAR gamma; zRAR-gamma-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.