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    chsy3 chondroitin sulfate synthase 3 [ Danio rerio (zebrafish) ]

    Gene ID: 368477, updated on 9-Dec-2024

    Summary

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    Official Symbol
    chsy3provided by ZNC
    Official Full Name
    chondroitin sulfate synthase 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-4
    See related
    Ensembl:ENSDARG00000069472 AllianceGenome:ZFIN:ZDB-GENE-030616-4
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:bac7cse.2; si:xx-bac7cse.2
    Summary
    Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process. Predicted to be located in membrane. Is expressed in several structures, including cranial cartilage; inner ear; lateral mesoderm; notochord; and tail bud. Orthologous to human CHSY3 (chondroitin sulfate synthase 3). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See chsy3 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (16592851..16608282)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (16634732..16650163)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase pim-3 Neighboring gene membrane integral NOTCH2 associated receptor 2 Neighboring gene uncharacterized LOC137496574 Neighboring gene stomatin (EPB72)-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development. Filipek-Górniok B, et al. Dev Dyn, 2013 Aug. PMID 23703795
    2. A subtracted cDNA library from the zebrafish (Danio rerio) embryonic inner ear. Coimbra RS, et al. Genome Res, 2002 Jun. PMID 12045154, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    chondroitin sulfate synthase 3
    NP_001082817.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089348.1 → NP_001082817.1  chondroitin sulfate synthase 3

      See identical proteins and their annotated locations for NP_001082817.1

      Status: PROVISIONAL

      Source sequence(s)
      BC134906
      UniProtKB/TrEMBL
      A0A8M1NE32, A4IG33
      Related
      ENSDARP00000147734.1, ENSDART00000187508.1
      Conserved Domains (2) summary
      cl11394
      Location:264 → 298
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
      cl21608
      Location:110 → 287
      Galactosyl_T; Galactosyltransferase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      16592851..16608282
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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