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    ascc2 activating signal cointegrator 1 complex subunit 2 [ Danio rerio (zebrafish) ]

    Gene ID: 393414, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ascc2provided by ZNC
    Official Full Name
    activating signal cointegrator 1 complex subunit 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1223
    See related
    Ensembl:ENSDARG00000013058 AllianceGenome:ZFIN:ZDB-GENE-040426-1223
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:63666
    Summary
    Predicted to enable ubiquitin binding activity. Predicted to be involved in regulation of DNA-templated transcription. Orthologous to human ASCC2 (activating signal cointegrator 1 complex subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ascc2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (18012140..18035585)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (17508155..17531584)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene si:dkey-112e17.1 Neighboring gene uncharacterized LOC137495574 Neighboring gene zinc finger DHHC-type palmitoyltransferase 8b Neighboring gene uncharacterized LOC110439809 Neighboring gene ring finger protein 215 Neighboring gene histone cell cycle regulator a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Transcriptional response of zebrafish larvae exposed to lindane reveals two detoxification genes of ABC transporter family (abcg5 and abcg8). Zhang L, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2020 Jun. PMID 32244031
    2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC63666

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    activating signal cointegrator 1 complex subunit 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200442.1 → NP_956736.1  activating signal cointegrator 1 complex subunit 2

      See identical proteins and their annotated locations for NP_956736.1

      Status: PROVISIONAL

      Source sequence(s)
      BC054929
      UniProtKB/TrEMBL
      Q7SYC1
      Related
      ENSDARP00000048858.4, ENSDART00000048859.6
      Conserved Domains (1) summary
      cd14364
      Location:479 → 518
      CUE_ASCC2; CUE domain found in activating signal cointegrator 1 complex subunit 2 (ASCC2) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      18012140..18035585
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165069.5 → XP_005165126.1  activating signal cointegrator 1 complex subunit 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BC77, A2CEX4
      Conserved Domains (1) summary
      cd14364
      Location:479 → 518
      CUE_ASCC2; CUE domain found in activating signal cointegrator 1 complex subunit 2 (ASCC2) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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