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    atp10b ATPase phospholipid transporting 10B [ Danio rerio (zebrafish) ]

    Gene ID: 563932, updated on 4-Jan-2025

    Summary

    Official Symbol
    atp10bprovided by ZNC
    Official Full Name
    ATPase phospholipid transporting 10Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-130530-796
    See related
    Ensembl:ENSDARG00000076230 AllianceGenome:ZFIN:ZDB-GENE-130530-796
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Predicted to be involved in phospholipid translocation. Predicted to act upstream of or within phospholipid transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human ATP10B (ATPase phospholipid transporting 10B (putative)). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See atp10b in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (22297150..22363362)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (21999894..22065021)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha6a Neighboring gene gamma-aminobutyric acid type A receptor subunit beta2a Neighboring gene uncharacterized LOC103908748 Neighboring gene F-box and leucine-rich repeat protein 3, like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATPase-coupled intramembrane lipid transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ATPase-coupled intramembrane lipid transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in phospholipid translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within phospholipid transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    probable phospholipid-transporting ATPase VB; phospholipid-transporting ATPase VB
    Names
    ATPase, class V, type 10B
    zmp:0000000793
    XP_017214606.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      22297150..22363362
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017359117.3XP_017214606.1  phospholipid-transporting ATPase VB

      UniProtKB/TrEMBL
      A0A0R4ILC3, A0A8M6Z488, E7FFI1
      Related
      ENSDARP00000100145.4, ENSDART00000113676.4
      Conserved Domains (6) summary
      TIGR01652
      Location:461258
      ATPase-Plipid; phospholipid-translocating P-type ATPase, flippase
      pfam13246
      Location:656738
      Cation_ATPase; Cation transport ATPase (P-type)
      pfam16209
      Location:3895
      PhoLip_ATPase_N; Phospholipid-translocating ATPase N-terminal
      pfam16212
      Location:10061251
      PhoLip_ATPase_C; Phospholipid-translocating P-type ATPase C-terminal
      cl00297
      Location:793856
      R3H; R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich ...
      cl21460
      Location:9601006
      HAD_like; Haloacid Dehalogenase-like Hydrolases