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    stox2a storkhead box 2a [ Danio rerio (zebrafish) ]

    Gene ID: 571741, updated on 4-Jan-2025

    Summary

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    Official Symbol
    stox2aprovided by ZNC
    Official Full Name
    storkhead box 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090313-101
    See related
    Ensembl:ENSDARG00000070162 AllianceGenome:ZFIN:ZDB-GENE-090313-101
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    stox2; si:ch211-261d5.6
    Summary
    Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm and nucleus. Orthologous to human STOX2 (storkhead box 2). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See stox2a in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (39898592..39977206, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (39180519..39259298, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene interferon regulatory factor 2a Neighboring gene transmembrane protein 134 Neighboring gene superoxide dismutase 3, extracellular b Neighboring gene inhibitor of growth family, member 2 Neighboring gene aryl hydrocarbon receptor interacting protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    storkhead-box protein 2
    Names
    storkhead box 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      39898592..39977206 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001922863.8 → XP_001922898.3  storkhead-box protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M1QKU0, F1QWT9
      Related
      ENSDARP00000122521.2, ENSDART00000139354.3
      Conserved Domains (1) summary
      pfam10264
      Location:117 → 193
      Stork_head; Winged helix Storkhead-box1 domain

    2. XM_005160006.5 → XP_005160063.1  storkhead-box protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M2B6V2, F8W5K8
      Related
      ENSDARP00000125060.1, ENSDART00000149730.3
      Conserved Domains (1) summary
      pfam10264
      Location:68 → 144
      Stork_head; Winged helix Storkhead-box1 domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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