homer3b homer scaffold protein 3b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: homer3bprovided by ZNC
Official Full Name: homer scaffold protein 3bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-739
See related: Ensembl:ENSDARG00000010789 AllianceGenome:ZFIN:ZDB-GENE-040426-739
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: homer3; zgc:55557
Summary: Predicted to enable G protein-coupled glutamate receptor binding activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of store-operated calcium entry. Predicted to be located in synapse. Predicted to be active in several cellular components, including dendrite; plasma membrane; and postsynaptic density. Orthologous to human HOMER3 (homer scaffold protein 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (13424194..13505660)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (13366579..13447995)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled glutamate receptor binding	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled glutamate receptor binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G protein-coupled glutamate receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within G protein-coupled glutamate receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in regulation of store-operated calcium entry	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in dendrite	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in postsynaptic density	IBA Inferred from Biological aspect of Ancestor more info
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: homer protein homolog 3b

Names: homer homolog 3; homer scaffolding protein 3; homer scaffolding protein 3b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201113.1 → NP_957407.1 homer protein homolog 3b

See identical proteins and their annotated locations for NP_957407.1

Status: PROVISIONAL

Source sequence(s)

BC045383

UniProtKB/TrEMBL

Q7ZVW5

Related

ENSDARP00000106317.2, ENSDART00000125563.3

Conserved Domains (2) summary

cd01206
Location:3 → 111

EVH1_Homer_Vesl; Homer/Vesl family proteins EVH1 domain

pfam12269
Location:279 → 327

zf-CpG_bind_C; CpG binding protein zinc finger C terminal domain