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    serinc2 serine incorporator 2 [ Danio rerio (zebrafish) ]

    Gene ID: 569338, updated on 9-Dec-2024

    Summary

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    Official Symbol
    serinc2provided by ZNC
    Official Full Name
    serine incorporator 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041111-296
    See related
    Ensembl:ENSDARG00000056532 AllianceGenome:ZFIN:ZDB-GENE-041111-296
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7151765; si:ch211-232d9.2
    Summary
    Predicted to be active in membrane. Is expressed in EVL; ectoderm; notochord; peripheral olfactory organ; and pronephric duct. Orthologous to human SERINC2 (serine incorporator 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See serinc2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (15408363..15420718, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (15504001..15516356, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene endothelin 2 Neighboring gene HIVEP zinc finger 3a Neighboring gene antifreeze protein Maxi-like Neighboring gene finTRIM family, member 55 Neighboring gene lin-28 homolog Ab

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Transcriptional regulation in liver and testis associated with developmental and reproductive effects in male zebrafish exposed to natural mixtures of persistent organic pollutants (POP). Nourizadeh-Lillabadi R, et al. J Toxicol Environ Health A, 2009. PMID 19184727
    2. Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision. Volkov LI, et al. Proc Natl Acad Sci U S A, 2020 Jun 30. PMID 32541022, Free PMC Article
    3. Coherent but overlapping expression of microRNAs and their targets during vertebrate development. Shkumatava A, et al. Genes Dev, 2009 Feb 15. PMID 19240133, Free PMC Article
    4. Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. Sundström G, et al. PLoS One, 2010 May 6. PMID 20463905, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine incorporator 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045182.1 → NP_001038647.1  serine incorporator 2 precursor

      Status: PROVISIONAL

      Source sequence(s)
      BX322664
      UniProtKB/TrEMBL
      A0A8M1NA28, Q1LXL6
      Related
      ENSDARP00000026726.7, ENSDART00000027697.9
      Conserved Domains (1) summary
      pfam03348
      Location:17 → 456
      Serinc; Serine incorporator (Serinc)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      15408363..15420718 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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