eri1 exoribonuclease 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eri1provided by ZNC
Official Full Name: exoribonuclease 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-39
See related: Ensembl:ENSDARG00000044692 AllianceGenome:ZFIN:ZDB-GENE-050522-39
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: thex1; zgc:110635
Summary: Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to be involved in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within regulatory ncRNA-mediated gene silencing. Predicted to be active in cytoplasm and nucleolus. Orthologous to human ERI1 (exoribonuclease 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (19907763..19915900, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (19871125..19879264, complement)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

fc24f09.y1 (e-PCR)
- UniSTS:193210

fd20c10.x1 (e-PCR)
- UniSTS:204271

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 3'-5'-RNA exonuclease activity	IBA Inferred from Biological aspect of Ancestor more info
enables 3'-5'-RNA exonuclease activity	IEA Inferred from Electronic Annotation more info
enables exonuclease activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nuclease activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulatory ncRNA-mediated gene silencing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 3'-5' exoribonuclease 1

Names: three prime histone mRNA exonuclease 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020614.1 → NP_001018450.1 3'-5' exoribonuclease 1

See identical proteins and their annotated locations for NP_001018450.1

Status: PROVISIONAL

Source sequence(s)

BC095343

UniProtKB/TrEMBL

A0A2R8QDC1, F6NW04, Q503G0

Related

ENSDARP00000065670.5, ENSDART00000065671.7

Conserved Domains (2) summary

cd06133
Location:118 → 298

ERI-1_3'hExo_like; DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins

pfam02037
Location:62 → 96

SAP; SAP domain