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    tmem18 transmembrane protein 18 [ Danio rerio (zebrafish) ]

    Gene ID: 449559, updated on 9-Dec-2024

    Summary

    Official Symbol
    tmem18provided by ZNC
    Official Full Name
    transmembrane protein 18provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040927-26
    See related
    Ensembl:ENSDARG00000036704 AllianceGenome:ZFIN:ZDB-GENE-040927-26
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:101011
    Summary
    Predicted to enable DNA binding activity. Acts upstream of or within fat cell differentiation. Predicted to be located in membrane and nucleus. Predicted to be active in nuclear membrane. Is expressed in gill; heart; liver; nervous system; and pleuroperitoneal region. Orthologous to human TMEM18 (transmembrane protein 18). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See tmem18 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (35642074..35648952, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (35543271..35550149, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene ALK and LTK ligand 2a Neighboring gene uncharacterized LOC137489143 Neighboring gene cyclin T1 Neighboring gene premelanosome protein b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within fat cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005601.2NP_001005601.1  transmembrane protein 18

      See identical proteins and their annotated locations for NP_001005601.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082297
      UniProtKB/Swiss-Prot
      Q641M3
      Related
      ENSDARP00000053309.2, ENSDART00000053310.3
      Conserved Domains (1) summary
      pfam14770
      Location:25143
      TMEM18; Transmembrane protein 18

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      35642074..35648952 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)