U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    pds5b PDS5 cohesin associated factor B [ Danio rerio (zebrafish) ]

    Gene ID: 565592, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    pds5bprovided by ZNC
    Official Full Name
    PDS5 cohesin associated factor Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091217-2
    See related
    Ensembl:ENSDARG00000098897 AllianceGenome:ZFIN:ZDB-GENE-091217-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in DNA repair and mitotic sister chromatid cohesion. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed in several structures, including cranium; digestive system; nervous system; optic cup; and otic vesicle. Orthologous to human PDS5B (PDS5 cohesin associated factor B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See pds5b in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (33744549..33807687, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (33886568..33949719, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene histone deacetylase 12 Neighboring gene tRNA methyltransferase 9B Neighboring gene NEDD4 binding protein 2-like 2 Neighboring gene matrix metallopeptidase 13b

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Expression of cohesin and condensin genes during zebrafish development supports a non-proliferative role for cohesin. Mönnich M, et al. Gene Expr Patterns, 2009 Dec. PMID 19723591
    2. High-throughput genome editing and phenotyping facilitated by high resolution melting curve analysis. Thomas HR, et al. PLoS One, 2014. PMID 25503746, Free PMC Article
    3. Genomic organization and evolution of olfactory receptors and trace amine-associated receptors in channel catfish, Ictalurus punctatus. Gao S, et al. Biochim Biophys Acta Gen Subj, 2017 Mar. PMID 27773705
    4. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within mitotic sister chromatid cohesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    sister chromatid cohesion protein PDS5 homolog B
    Names
    PDS5, regulator of cohesion maintenance, homolog B

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      33744549..33807687 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_688861.8 → XP_693953.2  sister chromatid cohesion protein PDS5 homolog B

      UniProtKB/TrEMBL
      A0A0R4IP12, A0A8N7UVY5
      Related
      ENSDARP00000136712.1, ENSDART00000158445.2
      Conserved Domains (2) summary
      pfam08143
      Location:1229 → 1272
      CBFNT; CBFNT (NUC161) domain
      sd00044
      Location:240 → 261
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools