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    btr16 bloodthirsty-related gene family, member 16 [ Danio rerio (zebrafish) ]

    Gene ID: 767728, updated on 9-Dec-2024

    Summary

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    Official Symbol
    btr16provided by ZNC
    Official Full Name
    bloodthirsty-related gene family, member 16provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-1066
    See related
    Ensembl:ENSDARG00000028850 AllianceGenome:ZFIN:ZDB-GENE-060929-1066
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:154038; si:ch211-247l8.6
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be located in cytoplasm. Orthologous to several human genes including TRIM11 (tripartite motif containing 11); TRIM17 (tripartite motif containing 17); and TRIM21 (tripartite motif containing 21). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See btr16 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (18198878..18209747, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (18263488..18273701, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene bloodthirsty-related gene family, member 14 Neighboring gene E3 ubiquitin-protein ligase TRIM39-like Neighboring gene si:ch211-247l8.10 Neighboring gene odorant receptor, family 91, subfamily A, member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish. van der Aa LM, et al. BMC Biol, 2009 Feb 5. PMID 19196451, Free PMC Article
    2. Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfish. Boudinot P, et al. PLoS One, 2011. PMID 21789205, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC154038

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    bloodthirsty-related gene family, member 16

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076666.2 → NP_001070134.2  bloodthirsty-related gene family, member 16

      Status: VALIDATED

      Source sequence(s)
      CR388163
      Related
      ENSDARP00000120795.1, ENSDART00000141508.3

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      18198878..18209747 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005157455.5 → XP_005157512.1  bloodthirsty-related gene family, member 16 isoform X1

      See identical proteins and their annotated locations for XP_005157512.1

      UniProtKB/TrEMBL
      A0A8M2B489
      Related
      ENSDARP00000113503.1, ENSDART00000136280.2
      Conserved Domains (4) summary
      cd00162
      Location:18 → 62
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00643
      Location:144 → 180
      zf-B_box; B-box zinc finger
      pfam14661
      Location:220 → 288
      HAUS6_N; HAUS augmin-like complex subunit 6 N-terminus
      cd13733
      Location:356 → 529
      SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty

    2. XM_068213587.1 → XP_068069688.1  bloodthirsty-related gene family, member 16 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B489
    Nucleotide Protein Strain
    Heading Accession and Version

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