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    foxg1b forkhead box G1b [ Danio rerio (zebrafish) ]

    Gene ID: 405850, updated on 9-Dec-2024

    Summary

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    Official Symbol
    foxg1bprovided by ZNC
    Official Full Name
    forkhead box G1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2437
    See related
    Ensembl:ENSDARG00000032705 AllianceGenome:ZFIN:ZDB-GENE-040426-2437
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:85969
    Summary
    Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in anterior neural plate; immature eye; retina; and telencephalon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See foxg1b in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (43114108..43116250)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (42822027..42824169)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496737 Neighboring gene EMAP like 6 Neighboring gene acylphosphatase 2, muscle type Neighboring gene spectrin, beta, non-erythrocytic 1 Neighboring gene uncharacterized LOC137496738

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinct expression of two foxg1 paralogues in zebrafish. Zhao XF, et al. Gene Expr Patterns, 2009 Jun. PMID 19379839
    2. Emergence of Neuronal Diversity during Vertebrate Brain Development. Raj B, et al. Neuron, 2020 Dec 23. PMID 33068532, Free PMC Article
    3. Impaired neural development in a zebrafish model for Lowe syndrome. Ramirez IB, et al. Hum Mol Genet, 2012 Apr 15. PMID 22210625, Free PMC Article
    4. Mapping single-cell atlases throughout Metazoa unravels cell type evolution. Tarashansky AJ, et al. Elife, 2021 May 4. PMID 33944782, Free PMC Article
    5. The Dlx5 and Foxg1 transcription factors, linked via miRNA-9 and -200, are required for the development of the olfactory and GnRH system. Garaffo G, et al. Mol Cell Neurosci, 2015 Sep. PMID 25937343, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC85969

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    forkhead box protein G1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212914.1 → NP_998079.2  forkhead box protein G1b

      Status: VALIDATED

      Source sequence(s)
      BC067725
      UniProtKB/TrEMBL
      A0A8M1PIB6, F6NTK8, Q6NW50
      Related
      ENSDARP00000020080.7, ENSDART00000013642.7
      Conserved Domains (1) summary
      smart00339
      Location:77 → 165
      FH; FORKHEAD

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      43114108..43116250
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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