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    fbxo11b F-box protein 11b [ Danio rerio (zebrafish) ]

    Gene ID: 567742, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fbxo11bprovided by ZNC
    Official Full Name
    F-box protein 11bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-110810-2
    See related
    Ensembl:ENSDARG00000061631 AllianceGenome:ZFIN:ZDB-GENE-110810-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fbxo11-like
    Summary
    Predicted to enable zinc ion binding activity. Human ortholog(s) of this gene implicated in breast carcinoma and lung non-small cell carcinoma. Orthologous to human FBXO11 (F-box protein 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See fbxo11b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (24841719..24904944, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (24720500..24784034, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene golgin subfamily A member 6-like protein 1 Neighboring gene forkhead box N2b Neighboring gene mutS homolog 2 (E. coli) Neighboring gene calmodulin 2b, (phosphorylase kinase, delta)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Molecular characterisation and inductive expression of a fish protein arginine methyltransferase 1 gene in response to virus infection. Dong CW, et al. Fish Shellfish Immunol, 2007 Apr. PMID 17055744
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    F-box only protein 11
    Names
    F-box only protein 11-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      24841719..24904944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_691042.10 → XP_696134.3  F-box only protein 11 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PME1, U3JA39
      Related
      ENSDARP00000127104.1, ENSDART00000153436.2
      Conserved Domains (3) summary
      pfam12937
      Location:109 → 152
      F-box-like
      pfam13229
      Location:616 → 775
      Beta_helix; Right handed beta helix region
      cl19744
      Location:802 → 843
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    2. XM_005156232.5 → XP_005156289.1  F-box only protein 11 isoform X2

      See identical proteins and their annotated locations for XP_005156289.1

      UniProtKB/TrEMBL
      A0A8M9QEP9
      Conserved Domains (3) summary
      pfam12937
      Location:73 → 116
      F-box-like
      pfam13229
      Location:580 → 739
      Beta_helix; Right handed beta helix region
      cl19744
      Location:766 → 807
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394844.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      180180..242211 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021472548.2 → XP_021328223.1  F-box only protein 11 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PME1, U3JA39
      Conserved Domains (3) summary
      pfam12937
      Location:109 → 152
      F-box-like
      pfam13229
      Location:616 → 775
      Beta_helix; Right handed beta helix region
      cl19744
      Location:802 → 843
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    2. XM_021472549.2 → XP_021328224.1  F-box only protein 11 isoform X2

      UniProtKB/TrEMBL
      A0A8M9QEP9
      Conserved Domains (3) summary
      pfam12937
      Location:73 → 116
      F-box-like
      pfam13229
      Location:580 → 739
      Beta_helix; Right handed beta helix region
      cl19744
      Location:766 → 807
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
    Nucleotide Protein
    Heading Accession and Version

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