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    tesk1b testis associated actin remodelling kinase 1b [ Danio rerio (zebrafish) ]

    Gene ID: 559449, updated on 9-Dec-2024

    Summary

    Official Symbol
    tesk1bprovided by ZNC
    Official Full Name
    testis associated actin remodelling kinase 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7512
    See related
    Ensembl:ENSDARG00000079281 AllianceGenome:ZFIN:ZDB-GENE-030131-7512
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj22e11; wu:fj22e11; si:dkeyp-75h12.2
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of stress fiber assembly. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human TESK1 (testis associated actin remodelling kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See tesk1b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (24528866..24571456)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (24256978..24300295)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene negative elongation factor complex member A Neighboring gene fatty acid amide hydrolase 2b Neighboring gene bloodthirsty-related gene family, member 9 Neighboring gene si:dkeyp-75h12.7 Neighboring gene uncharacterized LOC137490272

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine/tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of stress fiber assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    dual specificity testis-specific protein kinase 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      24528866..24571456
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477792.2XP_021333467.1  dual specificity testis-specific protein kinase 2

      UniProtKB/TrEMBL
      A0A8M9PPL6, E7FEW6
      Related
      ENSDARP00000150286.1, ENSDART00000180552.1
      Conserved Domains (1) summary
      cl21453
      Location:54302
      PKc_like; Protein Kinases, catalytic domain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394689.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      172773..215363
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009303137.4XP_009301412.1  dual specificity testis-specific protein kinase 2

      See identical proteins and their annotated locations for XP_009301412.1

      UniProtKB/TrEMBL
      A0A8M9PPL6, E7FEW6
      Conserved Domains (1) summary
      cl21453
      Location:54302
      PKc_like; Protein Kinases, catalytic domain