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    npat nuclear protein, ataxia-telangiectasia locus [ Danio rerio (zebrafish) ]

    Gene ID: 552973, updated on 9-Dec-2024

    Summary

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    Official Symbol
    npatprovided by ZNC
    Official Full Name
    nuclear protein, ataxia-telangiectasia locusprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050506-54
    See related
    Ensembl:ENSDARG00000055548 AllianceGenome:ZFIN:ZDB-GENE-050506-54
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:6901964
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be active in nucleus. Orthologous to human NPAT (nuclear protein, coactivator of histone transcription). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See npat in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (25528294..25542592)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (25593020..25607548)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene zgc:152863 Neighboring gene hypoxia inducible factor 1 subunit alpha, like Neighboring gene matrix metallopeptidase 20a (enamelysin) Neighboring gene matrix metallopeptidase 20b (enamelysin)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The 13q and 11q B-cell chronic lymphocytic leukaemia-associated regions derive from a common ancestral region in the zebrafish. Auer RL, et al. Br J Haematol, 2007 Jun. PMID 17488487
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein NPAT
    Names
    zmp:0000000655

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      25528294..25542592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_685884.8 → XP_690976.4  protein NPAT

      UniProtKB/TrEMBL
      A0A0R4IH22, A0A8N7TB69
      Related
      ENSDARP00000133803.1, ENSDART00000123143.3
      Conserved Domains (1) summary
      pfam15712
      Location:662 → 1310
      NPAT_C; NPAT C terminus
    Nucleotide Protein Strain
    Heading Accession and Version

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