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    irg1l immunoresponsive gene 1, like [ Danio rerio (zebrafish) ]

    Gene ID: 562007, updated on 4-Jan-2025

    Summary

    Official Symbol
    irg1lprovided by ZNC
    Official Full Name
    immunoresponsive gene 1, likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061103-301
    See related
    Ensembl:ENSDARG00000062788 AllianceGenome:ZFIN:ZDB-GENE-061103-301
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc49d01; wu:fc49d01; zgc:154020
    Summary
    Predicted to enable aconitate decarboxylase activity. Acts upstream of or within inflammatory response to wounding and response to bacterium. Predicted to be active in mitochondrion. Is expressed in digestive system; head; and male organism. [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See irg1l in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (11427052..11430555, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (11121038..11124541, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene MAP7 domain-containing protein 1-like Neighboring gene glyoxalase domain containing 5 Neighboring gene si:ch211-153b23.3 Neighboring gene si:ch211-153b23.4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC154020

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables aconitate decarboxylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in defense response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within inflammatory response to wounding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    immunoresponsive gene 1, like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077607.1NP_001071075.1  immunoresponsive gene 1, like

      See identical proteins and their annotated locations for NP_001071075.1

      Status: PROVISIONAL

      Source sequence(s)
      BC125936
      UniProtKB/TrEMBL
      A0A8N7UYD9, A0JMM8
      Related
      ENSDARP00000085591.4, ENSDART00000091158.5
      Conserved Domains (1) summary
      pfam03972
      Location:42485
      MmgE_PrpD; MmgE/PrpD family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      11427052..11430555 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)