arpc5b actin related protein 2/3 complex, subunit 5B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: arpc5bprovided by ZNC
Official Full Name: actin related protein 2/3 complex, subunit 5Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040120-7
See related: Ensembl:ENSDARG00000019062 AllianceGenome:ZFIN:ZDB-GENE-040120-7
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation and cell migration. Predicted to act upstream of or within regulation of actin filament polymerization. Predicted to be located in actin cytoskeleton; cell projection; and nucleus. Predicted to be part of Arp2/3 protein complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human ARPC5 (actin related protein 2/3 complex subunit 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 20

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (34151685..34155611)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (34248806..34252732)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fa95d10.y1 (e-PCR)
- UniSTS:189702

fl09c06.x1 (e-PCR)
- UniSTS:201951

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin filament binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in Arp2/3 complex-mediated actin nucleation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within Arp2/3 complex-mediated actin nucleation	IEA Inferred from Electronic Annotation more info
involved_in cell migration	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of actin filament polymerization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Arp2/3 protein complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Arp2/3 protein complex	IEA Inferred from Electronic Annotation more info
located_in actin cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: actin-related protein 2/3 complex subunit 5b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.