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    nfo endonuclease IV [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946669, updated on 3-Dec-2024

    Summary

    Official Symbol
    nfo
    Official Full Name
    endonuclease IV
    Primary source
    ECOCYC:EG10651
    Locus tag
    b2159
    See related
    ASAP:ABE-0007146
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2152
    Summary
    Damaged bases in DNA occur due to alkylating agents, ionizing radiation or oxidants such as superoxide radicals, hydrogen peroxide and hydroxyl radicals. [More information is available at EcoCyc: EG10651].
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    Genomic context

    Sequence:
    NC_000913.3 (2250840..2251697)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional regulator YeiE Neighboring gene PF03601 family inner membrane protein YeiH Neighboring gene putative sugar kinase YeiI Neighboring gene putative nucleoside transporter

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 3'-5'-DNA exonuclease activity PubMed 
    enables DNA binding  
    enables DNA-(apurinic or apyrimidinic site) endonuclease activity  
    enables DNA-(apurinic or apyrimidinic site) endonuclease activity PubMed 
    enables deoxyribonuclease IV (phage-T4-induced) activity  
    enables endonuclease activity PubMed 
    enables endonuclease activity  
    enables metal ion binding  
    enables phosphatase activity PubMed 
    enables phosphoric diester hydrolase activity  
    enables phosphoric diester hydrolase activity PubMed 
    enables zinc ion binding PubMed 
    enables zinc ion binding  
    Process Evidence Code Pubs
    involved_in DNA repair  
    acts_upstream_of_or_within DNA repair PubMed 
    involved_in base-excision repair  
    acts_upstream_of_or_within base-excision repair PubMed 
    Component Evidence Code Pubs
    located_in cytosol PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2250840..2251697
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416664.1 endonuclease IV [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416664.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6C9Q7X6
      Conserved Domains (1) summary
      PRK01060
      Location:1282
      PRK01060; endonuclease IV; Provisional
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