U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Zfp275 zinc finger protein 275 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293849, updated on 27-Nov-2024

    Summary

    Official Symbol
    Zfp275provided by RGD
    Official Full Name
    zinc finger protein 275provided by RGD
    Primary source
    RGD:1564630
    See related
    EnsemblRapid:ENSRNOG00000061073 AllianceGenome:RGD:1564630
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564630
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF275 (zinc finger protein 275). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 66.6), Adrenal (RPKM 59.5) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Zfp275 in Genome Data Viewer
    Location:
    Xq37
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (156208873..156225732)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (151057530..151074392)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (157457399..157474263, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene dnaJ homolog subfamily C member 8-like Neighboring gene PWWP domain containing 4 Neighboring gene U2 spliceosomal RNA Neighboring gene PNMA family member 6E Neighboring gene ZFP92 zinc finger protein Neighboring gene potassium two pore domain channel subfamily K member 6, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106343.1NP_001099813.1  zinc finger protein 275

      See identical proteins and their annotated locations for NP_001099813.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474099
      UniProtKB/TrEMBL
      A6KRY9, D3ZRH5
      Related
      ENSRNOP00000075303.1, ENSRNOT00000079860.3
      Conserved Domains (4) summary
      COG5048
      Location:252493
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:202274
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:365385
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:171191
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      156208873..156225732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099527.2XP_038955455.1  zinc finger protein 275 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:82341
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:213233
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_063279835.1XP_063135905.1  zinc finger protein 275 isoform X3

    3. XM_039099524.2XP_038955452.1  zinc finger protein 275 isoform X1

      UniProtKB/TrEMBL
      A6KRY9, D3ZRH5
      Conserved Domains (4) summary
      COG5048
      Location:252493
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:202274
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:365385
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:171191
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. XM_039099526.2XP_038955454.1  zinc finger protein 275 isoform X3

      Conserved Domains (4) summary
      COG5048
      Location:130371
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:80152
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:243263
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:4969
      ZF_C2H2; C2H2 Zn finger [structural motif]
    5. XM_039099528.2XP_038955456.1  zinc finger protein 275 isoform X3

      Conserved Domains (4) summary
      COG5048
      Location:130371
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:80152
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:243263
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:4969
      ZF_C2H2; C2H2 Zn finger [structural motif]
    6. XM_039099525.2XP_038955453.1  zinc finger protein 275 isoform X2

      Conserved Domains (4) summary
      COG5048
      Location:217458
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:167239
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:330350
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:136156
      ZF_C2H2; C2H2 Zn finger [structural motif]