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    Ltv1 LTV1 ribosome biogenesis factor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361452, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ltv1provided by RGD
    Official Full Name
    LTV1 ribosome biogenesis factorprovided by RGD
    Primary source
    RGD:1311264
    See related
    EnsemblRapid:ENSRNOG00000015217 AllianceGenome:RGD:1311264
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311264
    Summary
    Predicted to be involved in ribosomal small subunit biogenesis and ribosomal small subunit export from nucleus. Predicted to be located in nucleoplasm. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 135.0), Thymus (RPKM 130.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ltv1 in Genome Data Viewer
    Location:
    1p13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (9385834..9398557, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (7565673..7578398, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (7323043..7335766, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene keratin-associated protein 5-1-like Neighboring gene zinc finger, C2HC-type containing 1B Neighboring gene phosphatase and actin regulator 2 Neighboring gene alpha-L-fucosidase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal small subunit biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosome biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of preribosome, small subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein LTV1 homolog
    Names
    LTV1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014157.1NP_001014179.1  protein LTV1 homolog

      See identical proteins and their annotated locations for NP_001014179.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079397
      UniProtKB/Swiss-Prot
      Q68FR7
      UniProtKB/TrEMBL
      A0A8I5ZXR8
      Related
      ENSRNOP00000020453.4, ENSRNOT00000020453.8
      Conserved Domains (1) summary
      pfam04180
      Location:15440
      LTV; Low temperature viability protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      9385834..9398557 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)