Paqr7 progestin and adipoQ receptor family member 7 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Paqr7provided by RGD
Official Full Name: progestin and adipoQ receptor family member 7provided by RGD
Primary source: RGD:1563621
See related: EnsemblRapid:ENSRNOG00000022054 AllianceGenome:RGD:1563621
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable nuclear steroid receptor activity and steroid binding activity. Predicted to be involved in response to steroid hormone. Predicted to be active in plasma membrane. Orthologous to human PAQR7 (progestin and adipoQ receptor family member 7). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 349.8), Liver (RPKM 245.4) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q36

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (151992849..152004267)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (146709159..146720577)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (152708782..152720230)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Paqr7 expression pattern is low and homogeneous in the hypothalamus and more abundant in thalamic nuclei, and is likely to regulate sensory and cognitive functions in forebrain tissues of female rats.
Title: Distribution of mRNAs encoding classical progestin receptor, progesterone membrane components 1 and 2, serpine mRNA binding protein 1, and progestin and ADIPOQ receptor family members 7 and 8 in rat forebrain.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nuclear steroid receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables steroid binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in oogenesis	IEA Inferred from Electronic Annotation more info
involved_in response to steroid hormone	IBA Inferred from Biological aspect of Ancestor more info
involved_in steroid hormone receptor signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: membrane progestin receptor alpha

Names: progestin and adipoQ receptor family member VII

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001415929.1 → NP_001402858.1 membrane progestin receptor alpha

Status: VALIDATED

Source sequence(s)

JAXUCZ010000005

UniProtKB/TrEMBL

A0A8I6ASL5, A6IT27

Related

ENSRNOP00000088197.1, ENSRNOT00000109336.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086023.1 Reference GRCr8

Range

151992849..152004267

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039110043.2 → XP_038965971.1 membrane progestin receptor alpha isoform X2

UniProtKB/TrEMBL

Q4PU88

Related

ENSRNOP00000022714.3, ENSRNOT00000022713.5

Conserved Domains (1) summary

pfam03006
Location:75 → 299

HlyIII; Haemolysin-III related
XM_039110042.2 → XP_038965970.2 membrane progestin receptor alpha isoform X1

UniProtKB/TrEMBL

G3V867