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    Mospd1 motile sperm domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317312, updated on 3-Dec-2024

    Summary

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    Official Symbol
    Mospd1provided by RGD
    Official Full Name
    motile sperm domain containing 1provided by RGD
    Primary source
    RGD:1359486
    See related
    EnsemblRapid:ENSRNOG00000066239 AllianceGenome:RGD:1359486
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human MOSPD1 (motile sperm domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 223.1), Muscle (RPKM 169.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mospd1 in Genome Data Viewer
    Location:
    Xq36
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (138019719..138047475, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (133100200..133127960, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (157745939..157774505)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene PABIR family member 2 Neighboring gene PABIR family member 3 Neighboring gene small nuclear ribonucleoprotein polypeptide E, pseudogene 1 Neighboring gene embryonic testis differentiation homolog C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Mospd1, a new player in mesenchymal versus epidermal cell differentiation. Thaler R, et al. J Cell Physiol, 2011 Oct. PMID 21792907
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    motile sperm domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014107.2 → NP_001014129.1  motile sperm domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001014129.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/Swiss-Prot
      Q5RJS6
      UniProtKB/TrEMBL
      A0A8L2Q064, A0A8L2R7H2, A6KUJ2
      Related
      ENSRNOP00000003192.5, ENSRNOT00000003192.8
      Conserved Domains (1) summary
      pfam00635
      Location:16 → 113
      Motile_Sperm; MSP (Major sperm protein) domain

    2. NM_001434093.1 → NP_001421022.1  motile sperm domain-containing protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/Swiss-Prot
      Q5RJS6
      UniProtKB/TrEMBL
      A0A8L2Q064, A0A8L2R7H2, A6KUJ2

    3. NM_001434094.1 → NP_001421023.1  motile sperm domain-containing protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021

    4. NM_001434095.1 → NP_001421024.1  motile sperm domain-containing protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A8I5Y568, A0A8I6AC24

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      138019719..138047475 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017602055.3 → XP_017457544.1  motile sperm domain-containing protein 1 isoform X4

      Conserved Domains (1) summary
      pfam00635
      Location:16 → 113
      Motile_Sperm; MSP (Major sperm protein) domain

    2. XM_006257634.5 → XP_006257696.1  motile sperm domain-containing protein 1 isoform X3

      Conserved Domains (1) summary
      pfam00635
      Location:16 → 113
      Motile_Sperm; MSP (Major sperm protein) domain

    3. XM_006257633.5 → XP_006257695.1  motile sperm domain-containing protein 1 isoform X2

      Related
      ENSRNOP00000076964.2, ENSRNOT00000102965.2
      Conserved Domains (1) summary
      pfam00635
      Location:16 → 113
      Motile_Sperm; MSP (Major sperm protein) domain

    4. XM_063280036.1 → XP_063136106.1  motile sperm domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8L2R7H2
      Related
      ENSRNOP00000112498.1, ENSRNOT00000161890.1

    5. XM_063280041.1 → XP_063136111.1  motile sperm domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8I5Y568, A0A8I6AC24

    6. XM_063280040.1 → XP_063136110.1  motile sperm domain-containing protein 1 isoform X3

    7. XM_063280039.1 → XP_063136109.1  motile sperm domain-containing protein 1 isoform X2

      UniProtKB/Swiss-Prot
      Q5RJS6
      UniProtKB/TrEMBL
      A0A8L2Q064, A0A8L2R7H2, A6KUJ2

    8. XM_063280037.1 → XP_063136107.1  motile sperm domain-containing protein 1 isoform X2

      UniProtKB/Swiss-Prot
      Q5RJS6
      UniProtKB/TrEMBL
      A0A8L2Q064, A0A8L2R7H2, A6KUJ2

    9. XM_063280038.1 → XP_063136108.1  motile sperm domain-containing protein 1 isoform X2

      UniProtKB/Swiss-Prot
      Q5RJS6
      UniProtKB/TrEMBL
      A0A8L2Q064, A0A8L2R7H2, A6KUJ2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5RJS6.1 GenPept UniProtKB/Swiss-Prot:Q5RJS6

    Gene LinkOut

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