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    Cd52 CD52 molecule [ Rattus norvegicus (Norway rat) ]

    Gene ID: 117054, updated on 27-Nov-2024

    Summary

    Official Symbol
    Cd52provided by RGD
    Official Full Name
    CD52 moleculeprovided by RGD
    Primary source
    RGD:620627
    See related
    EnsemblRapid:ENSRNOG00000015403 AllianceGenome:RGD:620627
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    B7
    Summary
    Predicted to be involved in positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within response to bacterium. Predicted to be located in plasma membrane and side of membrane. Predicted to be active in sperm midpiece. Orthologous to human CD52 (CD52 molecule). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 73.6), Lung (RPKM 14.4) and 3 other tissues See more
    Orthologs
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    Genomic context

    See Cd52 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (151603537..151605096, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (146319789..146321348, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (152322910..152324469, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134487000 Neighboring gene zinc finger protein 683 Neighboring gene crystallin beta-gamma domain containing 2 Neighboring gene ferritin light chain 1-like Neighboring gene UBX domain protein 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in sperm midpiece IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in sperm midpiece ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    CAMPATH-1 antigen
    Names
    CD52 antigen
    lymphocyte differentiation antigen B7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053983.2NP_446435.2  CAMPATH-1 antigen precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/Swiss-Prot
      Q63064
      UniProtKB/TrEMBL
      A6IT00
      Related
      ENSRNOP00000020688.4, ENSRNOT00000020688.6
      Conserved Domains (1) summary
      pfam15116
      Location:6296
      CD52; CAMPATH-1 antigen

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      151603537..151605096 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)