U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Npvf neuropeptide VF precursor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 60570, updated on 3-Dec-2024

    Summary

    Official Symbol
    Npvfprovided by RGD
    Official Full Name
    neuropeptide VF precursorprovided by RGD
    Primary source
    RGD:61815
    See related
    EnsemblRapid:ENSRNOG00000010806 AllianceGenome:RGD:61815
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rfrp
    Summary
    Enables signaling receptor binding activity. Involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Orthologous to human NPVF (neuropeptide VF precursor). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 10.1) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Npvf in Genome Data Viewer
    Location:
    4q24
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (81043128..81047045, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (79712358..79716275, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (80391785..80395476, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102546410 Neighboring gene cytochrome c, somatic Neighboring gene sperm microtubule inner protein 4 Neighboring gene uncharacterized LOC108350707 Neighboring gene aurora kinase A, pseudogene 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables neuropeptide activity IEA
    Inferred from Electronic Annotation
    more info
     
    NOT enables neuropeptide activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables neuropeptide activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables signaling receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of gonadotropin secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of gonadotropin secretion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of gonadotropin secretion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuropeptide signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in neuropeptide signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuropeptide signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    pro-FMRFamide-related neuropeptide VF
    Names
    FMRFamide-related peptides
    RFamide-related peptide

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023952.2NP_076442.2  pro-FMRFamide-related neuropeptide VF precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/Swiss-Prot
      Q920A3, Q9ESQ9
      UniProtKB/TrEMBL
      A6K0M5, G3V7F7
      Related
      ENSRNOP00000014437.4, ENSRNOT00000014437.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      81043128..81047045 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)