Cd7 Cd7 molecule [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cd7provided by RGD
Official Full Name: Cd7 moleculeprovided by RGD
Primary source: RGD:1310015
See related: EnsemblRapid:ENSRNOG00000036674 AllianceGenome:RGD:1310015
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in positive regulation of T cell cytokine production. Predicted to act upstream of or within homeostasis of number of cells within a tissue. Predicted to be located in membrane. Orthologous to human CD7 (CD7 molecule). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Thymus (RPKM 198.3), Spleen (RPKM 192.2) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q32.3

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (106802373..106805269, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (106304046..106306963, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (110229931..110232812, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables transmembrane signaling receptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within homeostasis of number of cells within a tissue	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of T cell cytokine production	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: T-cell antigen CD7

Names: CD7 antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107074.1 → NP_001100544.1 T-cell antigen CD7 precursor

See identical proteins and their annotated locations for NP_001100544.1

Status: PROVISIONAL

Source sequence(s)

CH473948

UniProtKB/TrEMBL

B2RZ54, F7F5G3

Related

ENSRNOP00000051817.2, ENSRNOT00000054934.6

Conserved Domains (2) summary

cd00096
Location:25 → 28

Ig; Ig strand A [structural motif]

cl11960
Location:27 → 125

Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086028.1 Reference GRCr8

Range

106802373..106805269 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039086226.2 → XP_038942154.1 T-cell antigen CD7 isoform X1

Conserved Domains (2) summary

cd00096
Location:12 → 17

Ig; Ig strand C' [structural motif]

cl11960
Location:11 → 71

Ig; Immunoglobulin domain