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    CG6959 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41434, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6959provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037956
    Locus tag
    Dmel_CG6959
    See related
    AllianceGenome:FB:FBgn0037956
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    6959; CT21563; Dmel\CG6959
    Summary
    Predicted to be active in membrane. Is expressed in adult head. Orthologous to several human genes including TPBG (trophoblast glycoprotein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6959 in Genome Data Viewer
    Location:
    86F9-86F11; 3-51 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11822702..11869460, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7648424..7695182, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene glorund Neighboring gene Cytochrome c oxidase subunit 5A Neighboring gene Kynurenine aminotransferase Neighboring gene uncharacterized protein Neighboring gene shadow Neighboring gene uncharacterized protein Neighboring gene methuselah-like 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An extracellular interactome of immunoglobulin and LRR proteins reveals receptor-ligand networks. Özkan E, et al. Cell, 2013 Jul 3. PMID 23827685, Free PMC Article
    2. Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells. Ramirez J, et al. PLoS One, 2015. PMID 26460970, Free PMC Article
    3. The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster. Jehrke L, et al. Sci Rep, 2018 Apr 18. PMID 29670218, Free PMC Article
    4. Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila. Meltzer H, et al. Nat Commun, 2019 May 8. PMID 31068592, Free PMC Article
    5. circRNA biogenesis competes with pre-mRNA splicing. Ashwal-Fluss R, et al. Mol Cell, 2014 Oct 2. PMID 25242144

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c11846242-11841121 mobile_element_type = transposon:BS{}1292

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6959-PA
    CG6959-PC
    connectin-like

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11822702..11869460 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141865.4 → NP_650122.1  uncharacterized protein Dmel_CG6959, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650122.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H9ZJL9, Q9VGH2
      Related
      FBpp0081991
      Conserved Domains (4) summary
      cd00116
      Location:116 → 224
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:70 → 96
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:186 → 245
      LRR_8; Leucine rich repeat
      cl15307
      Location:276 → 328
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

    2. NM_001144565.2 → NP_001138037.1  uncharacterized protein Dmel_CG6959, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138037.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H9ZJL9, Q9VGH2
      Conserved Domains (4) summary
      cd00116
      Location:116 → 224
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:70 → 96
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:186 → 245
      LRR_8; Leucine rich repeat
      cl15307
      Location:276 → 328
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZV5 Q8SZV5
    Q9VGH2 Q9VGH2

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