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    CG10907 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39331, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10907provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036207
    Locus tag
    Dmel_CG10907
    See related
    AllianceGenome:FB:FBgn0036207
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10907
    Summary
    Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in organism. Orthologous to human CWC27 (CWC27 spliceosome associated cyclophilin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10907 in Genome Data Viewer
    Location:
    68D6-68D6; 3-36 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11793514..11795418)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11786614..11788518)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol 3-kinase 68D Neighboring gene uncharacterized protein Neighboring gene twitchy Neighboring gene Kinesin-like protein at 68D Neighboring gene Glycine C-acetyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222, Free PMC Article
    2. spenito is required for sex determination in Drosophila melanogaster. Yan D, et al. Proc Natl Acad Sci U S A, 2015 Sep 15. PMID 26324914, Free PMC Article
    3. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    4. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article
    5. An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling. Vinayagam A, et al. Cell Rep, 2016 Sep 13. PMID 27626673, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome HDA PubMed 
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of precatalytic spliceosome HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10907-PA
    NP_648508.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11793514..11795418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140251.3 → NP_648508.1  uncharacterized protein Dmel_CG10907 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648508.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTN7
      Related
      FBpp0075761
      Conserved Domains (1) summary
      cd01925
      Location:8 → 178
      cyclophilin_CeCYP16-like; cyclophilin_CeCYP16-like: cyclophilin-type peptidylprolyl cis- trans isomerase) (PPIase) domain similar to Caenorhabditis elegans cyclophilin 16. C. elegans CeCYP-16, compared to the archetypal cyclophilin Human cyclophilin A has, a reduced ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTN7 Q9VTN7

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