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    RabX6 RabX6 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38084, updated on 17-Dec-2024

    Summary

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    Official Symbol
    RabX6provided by FlyBase
    Official Full Name
    RabX6provided by FlyBase
    Primary source
    FLYBASE:FBgn0035155
    Locus tag
    Dmel_CG12015
    See related
    AllianceGenome:FB:FBgn0035155
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12015; Dmel\CG12015; DmRabX6; rabx6; rabX6
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in several processes, including Rab protein signal transduction; autophagosome assembly; and intracellular protein transport. Located in neuronal cell body. Is expressed in several structures, including Bolwig organ; adult ensheathing glial cell; brain; imaginal disc; and synaptic neuropil domain. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RabX6 in Genome Data Viewer
    Location:
    61C8-61C8; 3-0.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (690517..691951)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (690517..691951)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene highroad Neighboring gene uncharacterized protein Neighboring gene Vesicle transport through interaction with t-SNAREs 1a Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44514

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High-resolution in situ hybridization analysis on the chromosomal interval 61C7-61C8 of Drosophila melanogaster reveals interbands as open chromatin domains. Zielke T, et al. Chromosoma, 2016 Jun. PMID 26520107
    2. The bantam gene regulates Drosophila growth. Hipfner DR, et al. Genetics, 2002 Aug. PMID 12196398, Free PMC Article
    3. A new genetic locus controlling growth and proliferation in Drosophila melanogaster. Raisin S, et al. Genetics, 2003 Jul. PMID 12871911, Free PMC Article
    4. Endosomal Rab GTPases regulate secretory granule maturation in Drosophila larval salivary glands. Ma CJ, et al. Commun Integr Biol, 2021 Feb 9. PMID 33628358, Free PMC Article
    5. Multiple Requirements for Rab GTPases in the Development of Drosophila Tracheal Dorsal Branches and Terminal Cells. Best BT, et al. G3 (Bethesda), 2020 Mar 5. PMID 31980432, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in Rab protein signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    RabX6
    Names
    CG12015-PA
    CG12015-PB
    RabX6-PA
    RabX6-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      690517..691951
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138208.4 → NP_612052.1  RabX6, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612052.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0N7
      Related
      FBpp0072476
      Conserved Domains (1) summary
      cd00154
      Location:10 → 172
      Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)

    2. NM_001274290.1 → NP_001261219.1  RabX6, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261219.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PE35
      Conserved Domains (2) summary
      smart00175
      Location:10 → 176
      RAB; Rab subfamily of small GTPases
      cd00154
      Location:10 → 172
      Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PE35 M9PE35
    Q9W0N7 Q9W0N7

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