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    Obp44a Odorant-binding protein 44a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35789, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Obp44aprovided by FlyBase
    Official Full Name
    Odorant-binding protein 44aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033268
    Locus tag
    Dmel_CG2297
    See related
    AllianceGenome:FB:FBgn0033268
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    44a; anon-EST:ParkEST107; bs11e05.y1; CG2297; DmelObp44a; Dmel\CG2297; obp44a
    Summary
    Predicted to enable odorant binding activity. Predicted to be involved in sensory perception of smell. Located in extracellular region. Is expressed in several structures, including adult head; adult heart; embryonic central brain neurons; ganglia; and larval nervous system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    See Obp44a in Genome Data Viewer
    Location:
    44B3-44B3; 2-58 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8134170..8135315, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4021675..4022820, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Nucleoporin 50kD Neighboring gene coilin Neighboring gene Suppressor of Cytokine Signaling at 44A Neighboring gene uncharacterized protein Neighboring gene PSEA-binding protein 49kD Neighboring gene Pabp2 Neighboring gene Lipin Neighboring gene kermit Neighboring gene long non-coding RNA:CR44068 Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression and purification of Drosophila OBP44a with the aids of LC-MS and NMR. He Y, et al. Protein Expr Purif, 2023 Dec. PMID 37597794, Free PMC Article
    2. Diverse biological processes coordinate the transcriptional response to nutritional changes in a Drosophila melanogaster multiparent population. Ng'oma E, et al. BMC Genomics, 2020 Jan 28. PMID 31992183, Free PMC Article
    3. Proteome profiling reveals tissue-specific protein expression in the male reproductive system of Drosophila melanogaster. Yamamoto MT, et al. Fly (Austin), 2010 Jan-Mar. PMID 20139713
    4. Selection and geography shape male reproductive tract transcriptomes in Drosophila melanogaster. Cridland JM, et al. Genetics, 2023 May 4. PMID 36869688, Free PMC Article
    5. Stochastic Modeling of Gene Expression Evolution Uncovers Tissue- and Sex-Specific Properties of Expression Evolution in the Drosophila Genus. Pal S, et al. J Comput Biol, 2023 Jan. PMID 36037023, Free PMC Article

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Odorant-binding protein 44a
    Names
    CG2297-PA
    CG2297-PB
    Obp44a-PA
    Obp44a-PB
    odorant-binding protein 44a

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      8134170..8135315 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299257.1 → NP_001286186.1  Odorant-binding protein 44a, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286186.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K084
      Conserved Domains (1) summary
      smart00708
      Location:32 → 132
      PhBP; Insect pheromone/odorant binding protein domains

    2. NM_136514.4 → NP_610358.1  Odorant-binding protein 44a, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610358.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K084
      Related
      FBpp0087892
      Conserved Domains (1) summary
      smart00708
      Location:32 → 132
      PhBP; Insect pheromone/odorant binding protein domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K084 Q7K084

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