Zmynd8 zinc finger, MYND-type containing 8 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zmynd8provided by RGD
Official Full Name: zinc finger, MYND-type containing 8provided by RGD
Primary source: RGD:1309544
See related: EnsemblRapid:ENSRNOG00000019154 AllianceGenome:RGD:1309544
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: spikar; Prkcbp1
Summary: Predicted to enable several functions, including histone binding activity; transcription corepressor activity; and zinc ion binding activity. Involved in several processes, including positive regulation of dendritic spine development; positive regulation of filopodium assembly; and regulation of postsynapse organization. Located in dendritic shaft and dendritic spine. Orthologous to human ZMYND8 (zinc finger MYND-type containing 8). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 88.3), Spleen (RPKM 79.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q42

Exon count:: 32

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (174948162..175061382, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (154528917..154629532, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (162480766..162594145, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH144094 (e-PCR)
- UniSTS:233340

RH136665 (e-PCR)
- UniSTS:218756

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables lysine-acetylated histone binding	ISO Inferred from Sequence Orthology more info
enables methylated histone binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein domain specific binding	ISO Inferred from Sequence Orthology more info
enables transcription corepressor activity	IBA Inferred from Biological aspect of Ancestor more info
enables transcription corepressor activity	ISO Inferred from Sequence Orthology more info
enables zinc ion binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in double-strand break repair via homologous recombination	ISO Inferred from Sequence Orthology more info
involved_in modulation of excitatory postsynaptic potential	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of cell migration	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in nervous system development	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of dendritic spine development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of dendritic spine maintenance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of filopodium assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of transcription elongation by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in protein localization to chromatin	ISO Inferred from Sequence Orthology more info
involved_in regulation of postsynaptic density protein 95 clustering	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chromatin	ISO Inferred from Sequence Orthology more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in dendritic shaft	IDA Inferred from Direct Assay more info	PubMed
located_in dendritic spine	IDA Inferred from Direct Assay more info	PubMed
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in site of DNA damage	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: MYND-type zinc finger-containing chromatin reader ZMYND8

Names: protein kinase C-binding protein 1; spikar delta C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001100838.2 → NP_001094308.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 2

See identical proteins and their annotated locations for NP_001094308.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

A0A8I5ZX36, A8C4G9

Related

ENSRNOP00000061219.1, ENSRNOT00000068328.4

Conserved Domains (6) summary

cd05841
Location:269 → 349

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:151 → 249

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:90 → 130

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:1038 → 1072

zf-MYND; MYND finger

pfam07798
Location:943 → 1034

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:426 → 622

DUF3544; Domain of unknown function (DUF3544)
NM_001431534.1 → NP_001418463.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

A0A8I5XZV4, A6JXG1
NM_001431535.1 → NP_001418464.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 3

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

A0A0G2K9F7
NM_001431536.1 → NP_001418465.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 4

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

A0A8I5ZX36
NM_001431537.1 → NP_001418466.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 5

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

A0A0G2K9F7
NM_001431538.1 → NP_001418467.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 6

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

A0A0G2K9F7
NM_001431539.1 → NP_001418468.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 7

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

Q5XI91
NM_001431540.1 → NP_001418469.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 8

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

Q5XI91
NM_001431541.1 → NP_001418470.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 9

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

K0J5S5, Q5XI91
NM_001431542.1 → NP_001418471.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 10

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

Q5XI91
NM_001431543.1 → NP_001418472.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform 11

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

Q5XI91

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086021.1 Reference GRCr8

Range

174948162..175061382 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063283406.1 → XP_063139476.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X20

UniProtKB/TrEMBL

A0A0G2K9F7
XM_063283402.1 → XP_063139472.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X13

UniProtKB/TrEMBL

A0A0G2K9F7
XM_006235571.5 → XP_006235633.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X23

UniProtKB/TrEMBL

A0A0G2K9F7

Conserved Domains (7) summary

cd05841
Location:264 → 344

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:146 → 244

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:85 → 125

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:898 → 932

zf-MYND; MYND finger

pfam07798
Location:803 → 894

DUF1640; Protein of unknown function (DUF1640)

pfam10243
Location:603 → 894

MIP-T3; Microtubule-binding protein MIP-T3

pfam12064
Location:421 → 617

DUF3544; Domain of unknown function (DUF3544)
XM_063283407.1 → XP_063139477.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X22

UniProtKB/TrEMBL

A0A0G2K9F7
XM_006235567.5 → XP_006235629.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X19

Conserved Domains (6) summary

cd05841
Location:264 → 344

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:146 → 244

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:85 → 125

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:982 → 1016

zf-MYND; MYND finger

pfam07798
Location:887 → 978

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:421 → 617

DUF3544; Domain of unknown function (DUF3544)
XM_006235564.5 → XP_006235626.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X14

Conserved Domains (6) summary

cd05841
Location:264 → 344

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:146 → 244

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:85 → 125

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:982 → 1016

zf-MYND; MYND finger

pfam07798
Location:887 → 978

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:421 → 617

DUF3544; Domain of unknown function (DUF3544)
XM_063283400.1 → XP_063139470.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X11
XM_006235555.5 → XP_006235617.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X6

UniProtKB/TrEMBL

A6JXG1

Conserved Domains (6) summary

cd05841
Location:264 → 344

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:146 → 244

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:85 → 125

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:1033 → 1067

zf-MYND; MYND finger

pfam07798
Location:938 → 1029

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:421 → 617

DUF3544; Domain of unknown function (DUF3544)
XM_006235569.5 → XP_006235631.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X21

UniProtKB/TrEMBL

A0A0G2K9F7

Conserved Domains (7) summary

cd05841
Location:289 → 369

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:171 → 269

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:110 → 150

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:923 → 957

zf-MYND; MYND finger

pfam07798
Location:828 → 919

DUF1640; Protein of unknown function (DUF1640)

pfam10243
Location:628 → 919

MIP-T3; Microtubule-binding protein MIP-T3

pfam12064
Location:446 → 642

DUF3544; Domain of unknown function (DUF3544)
XM_006235565.5 → XP_006235627.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X17

UniProtKB/TrEMBL

A0A0G2K9F7

Conserved Domains (6) summary

cd05841
Location:289 → 369

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:171 → 269

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:110 → 150

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:1007 → 1041

zf-MYND; MYND finger

pfam07798
Location:912 → 1003

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:446 → 642

DUF3544; Domain of unknown function (DUF3544)
XM_006235559.5 → XP_006235621.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X9

Conserved Domains (6) summary

cd05841
Location:289 → 369

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:171 → 269

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:110 → 150

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:1007 → 1041

zf-MYND; MYND finger

pfam07798
Location:912 → 1003

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:446 → 642

DUF3544; Domain of unknown function (DUF3544)
XM_063283398.1 → XP_063139468.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X8

UniProtKB/TrEMBL

A0A8I5ZX36
XM_006235541.5 → XP_006235603.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X2

Conserved Domains (6) summary

cd05841
Location:289 → 369

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:171 → 269

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:110 → 150

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:1058 → 1092

zf-MYND; MYND finger

pfam07798
Location:963 → 1054

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:446 → 642

DUF3544; Domain of unknown function (DUF3544)
XM_063283395.1 → XP_063139465.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X2

UniProtKB/TrEMBL

A0A8I5XZV4, A6JXG1

Related

ENSRNOP00000085787.2, ENSRNOT00000114990.2
XM_017591613.3 → XP_017447102.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X4

UniProtKB/TrEMBL

A6JXG1

Related

ENSRNOP00000076397.2, ENSRNOT00000116131.2

Conserved Domains (8) summary

cd05841
Location:269 → 349

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:151 → 249

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

COG5034
Location:4 → 133

TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]

cd15538
Location:90 → 130

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

cd06503
Location:965 → 1034

ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

pfam01753
Location:1038 → 1072

zf-MYND; MYND finger

pfam12064
Location:418 → 622

DUF3544; Domain of unknown function (DUF3544)

cl27544
Location:661 → 781

Herpes_glycop_D; Herpesvirus glycoprotein D/GG/GX domain
XM_063283404.1 → XP_063139474.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X16

UniProtKB/TrEMBL

A0A0G2K9F7
XM_063283396.1 → XP_063139466.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X5

UniProtKB/TrEMBL

A6JXG1
XM_017591609.3 → XP_017447098.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X1

UniProtKB/TrEMBL

A6JXG1

Related

ENSRNOP00000074980.3, ENSRNOT00000079324.3
XM_039104633.2 → XP_038960561.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X4

UniProtKB/TrEMBL

A6JXG1

Conserved Domains (8) summary

cd05841
Location:269 → 349

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:151 → 249

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

COG5034
Location:4 → 133

TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]

cd15538
Location:90 → 130

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

cd06503
Location:965 → 1034

ATP-synt_Fo_b; F-type ATP synthase, membrane subunit b

pfam01753
Location:1038 → 1072

zf-MYND; MYND finger

pfam12064
Location:418 → 622

DUF3544; Domain of unknown function (DUF3544)

cl27544
Location:661 → 781

Herpes_glycop_D; Herpesvirus glycoprotein D/GG/GX domain
XM_006235542.5 → XP_006235604.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X3

UniProtKB/TrEMBL

A6JXG1

Conserved Domains (6) summary

cd05841
Location:289 → 369

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:171 → 269

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:110 → 150

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:1058 → 1092

zf-MYND; MYND finger

pfam07798
Location:963 → 1054

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:446 → 642

DUF3544; Domain of unknown function (DUF3544)
XM_063283408.1 → XP_063139478.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X12

UniProtKB/TrEMBL

A6JXG1
XM_063283397.1 → XP_063139467.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X7

UniProtKB/TrEMBL

A6JXG1

Related

ENSRNOP00000084382.2, ENSRNOT00000103653.2
XM_063283405.1 → XP_063139475.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X18

UniProtKB/TrEMBL

A6JXG1
XM_063283403.1 → XP_063139473.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X15

UniProtKB/TrEMBL

A0A0G2K9F7
XM_006235560.5 → XP_006235622.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X10

UniProtKB/TrEMBL

A0A0G2K9F7

Related

ENSRNOP00000104801.1, ENSRNOT00000168449.1

Conserved Domains (6) summary

cd05841
Location:289 → 369

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

cd05508
Location:171 → 269

Bromo_RACK7; Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular ...

cd15538
Location:110 → 150

PHD_PRKCBP1; PHD finger found in protein kinase C-binding protein 1 (PRKCBP1)

pfam01753
Location:1007 → 1041

zf-MYND; MYND finger

pfam07798
Location:912 → 1003

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:446 → 642

DUF3544; Domain of unknown function (DUF3544)
XM_063283409.1 → XP_063139479.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X12

UniProtKB/TrEMBL

A6JXG1
XM_063283401.1 → XP_063139471.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X12

UniProtKB/TrEMBL

A6JXG1
XM_006235572.5 → XP_006235634.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X24

UniProtKB/TrEMBL

A6JXG1

Conserved Domains (5) summary

cd05841
Location:64 → 144

BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...

pfam01753
Location:833 → 867

zf-MYND; MYND finger

pfam07798
Location:738 → 829

DUF1640; Protein of unknown function (DUF1640)

pfam12064
Location:221 → 417

DUF3544; Domain of unknown function (DUF3544)

cl02556
Location:1 → 44

Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
XM_063283410.1 → XP_063139480.1 MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X25

UniProtKB/TrEMBL

Q5XI91