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    Rwdd1 RWD domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 259218, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rwdd1provided by RGD
    Official Full Name
    RWD domain containing 1provided by RGD
    Primary source
    RGD:631337
    See related
    EnsemblRapid:ENSRNOG00000042916 AllianceGenome:RGD:631337
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    sarip
    Summary
    Predicted to be involved in several processes, including androgen receptor signaling pathway; cellular response to testosterone stimulus; and positive regulation of androgen receptor activity. Predicted to be located in cytoplasm. Orthologous to human RWDD1 (RWD domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 134.5), Heart (RPKM 104.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rwdd1 in Genome Data Viewer
    Location:
    20q11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (26493664..26510282, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (25949723..25967147, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (27534361..27552225, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100910945 Neighboring gene uncharacterized LOC120098821 Neighboring gene tet methylcytosine dioxygenase 1 Neighboring gene trafficking protein particle complex subunit 3L Neighboring gene calcium homeostasis modulator family member 4 Neighboring gene calcium homeostasis modulator family member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of a novel thymus aging related protein Rwdd1. Kang N, et al. Cell Mol Immunol, 2008 Aug. PMID 18761815, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in androgen receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cellular response to oxidative stress ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cellular response to testosterone stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of androgen receptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    RWD domain-containing protein 1
    Names
    small androgen receptor-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_147146.2 → NP_671487.1  RWD domain-containing protein 1

      See identical proteins and their annotated locations for NP_671487.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ132390
      UniProtKB/Swiss-Prot
      Q99ND9
      UniProtKB/TrEMBL
      A0A8I6ACH0, A6K3S3
      Related
      ENSRNOP00000062656.4, ENSRNOT00000068777.5
      Conserved Domains (2) summary
      pfam05773
      Location:6 → 111
      RWD; RWD domain
      pfam16543
      Location:144 → 197
      DFRP_C; DRG Family Regulatory Proteins, Tma46

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      26493664..26510282 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008772869.4 → XP_008771091.1  RWD domain-containing protein 1 isoform X1

      Conserved Domains (1) summary
      pfam16543
      Location:48 → 101
      DFRP_C; DRG Family Regulatory Proteins, Tma46
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99ND9.1 GenPept UniProtKB/Swiss-Prot:Q99ND9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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